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awd - abnormal wing discs

Enables several functions, including magnesium ion binding activity; nucleoside diphosphate kinase activity; and purine ribonucleoside triphosphate binding activity. Involved in several processes, including adherens junction organization; establishment or maintenance of polarity of follicular epithelium; and open tracheal system development. Located in nuclear microtubule. Is expressed in several structures, including embryonic/larval midgut primordium; follicle cell; germline cell; mesoderm; and visceral mesoderm derivative. Human ortholog(s) of this gene implicated in neuroblastoma; ovary epithelial cancer; and teratoma. Orthologous to several human genes including NME2 (NME/NM23 nucleoside diphosphate kinase 2) and NME1-NME2 (NME1-NME2 readthrough). [provided by Alliance of Genome Resources, Nov 2024]

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Species Gene Architecture aa