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Ir100a Ionotropic receptor 100a [ Drosophila melanogaster (fruit fly) ]

Gene ID: 43753, updated on 9-Dec-2024

Summary

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Official Symbol
Ir100aprovided by FlyBase
Official Full Name
Ionotropic receptor 100aprovided by FlyBase
Primary source
FLYBASE:FBgn0039879
Locus tag
Dmel_CG11575
See related
AllianceGenome:FB:FBgn0039879
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
100a; CG11575; DmelIR100a; Dmel\CG11575; IR100a
Summary
Predicted to enable ligand-gated monoatomic ion channel activity. Involved in sensory perception of taste. Predicted to be located in membrane. Is expressed in dorsal cibarial sense organ neurons; labral sense organ neurons; larval gustatory receptor neuron of the dorsal pharyngeal sense organ; larval gustatory receptor neuron of the posterior pharyngeal sense organ; and posterior pharyngeal sense organ. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

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See Ir100a in Genome Data Viewer
Location:
100D2-100D2; 3-102 cM
Exon count:
1
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (31800963..31802774)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (27626685..27628496)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene fat facets Neighboring gene Methylcrotonoyl-CoA carboxylase 1 Neighboring gene ATP-dependent chromatin assembly factor large subunit Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Riboflavin transporter

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Combinatorial Pharyngeal Taste Coding for Feeding Avoidance in Adult Drosophila. Chen YD, et al. Cell Rep, 2019 Oct 22. PMID 31644916, Free PMC Article
  2. Peripheral Sensory Organs Contribute to Temperature Synchronization of the Circadian Clock in Drosophila melanogaster. George R, et al. Front Physiol, 2021. PMID 33603678, Free PMC Article
  3. A single pair of pharyngeal neurons functions as a commander to reject high salt in Drosophila melanogaster. Sang J, et al. Elife, 2024 Apr 4. PMID 38573740, Free PMC Article
  4. The multidimensional ionotropic receptors of Drosophila melanogaster. Rimal S, et al. Insect Mol Biol, 2018 Feb. PMID 28857341
  5. Avoiding cantharidin through ionotropic receptors. Pradhan RN, et al. J Hazard Mater, 2024 Mar 15. PMID 38278077

See all (30) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables ligand-gated monoatomic ion channel activity ISM
Inferred from Sequence Model
more info
 PubMed 
Process Evidence Code Pubs
involved_in detection of chemical stimulus ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
involved_in sensory perception of taste IEP
Inferred from Expression Pattern
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane ISM
Inferred from Sequence Model
more info
 PubMed 

General protein information

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Preferred Names
ionotropic receptor 100a
Names
CG11575-PA
Ir100a-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    31800963..31802774
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_143641.1 → NP_651898.2  ionotropic receptor 100a [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_651898.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9V9T2
    Related
    FBpp0085205, FBtr0085846
    Conserved Domains (2) summary
    pfam00060
    Location:439 → 580
    Lig_chan; Ligand-gated ion channel
    cl21456
    Location:210 → 255
    Periplasmic_Binding_Protein_Type_2; Type 2 periplasmic binding fold superfamily
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9V9T2 Q9V9T2

Gene LinkOut

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