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pho - pleiohomeotic

Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and chromatin DNA binding activity. Involved in several processes, including DNA topological change; dendrite morphogenesis; and regulation of gene expression. Located in chromatin; nucleus; and polytene chromosome puff. Part of Ino80 complex and PcG protein complex. Is expressed in organism. Human ortholog(s) of this gene implicated in congestive heart failure. Orthologous to several human genes including YY1 (YY1 transcription factor). [provided by Alliance of Genome Resources, Dec 2024]

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Species Gene Architecture aa