Pak - p21-activated kinase

Enables SH3 domain binding activity; protein serine/threonine kinase activity; and small GTPase binding activity. Involved in several processes, including autophagic cell death; dorsal closure, spreading of leading edge cells; and regulation of synapse organization. Located in several cellular components, including cell leading edge; lateral plasma membrane; and muscle cell postsynaptic specialization. Is active in neuromuscular junction. Colocalizes with actin filament and focal adhesion. Is expressed in several structures, including adult somatic muscle cell; amnioserosa; ganglia; head epidermis primordium; and tract. [provided by Alliance of Genome Resources, Nov 2024]

NCBI Orthologs

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