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Ran - Ran

Enables GTP binding activity. Involved in several processes, including microtubule cytoskeleton organization; nuclear pore complex assembly; and regulation of mitotic cell cycle. Located in cell cortex; mitotic spindle microtubule; and nucleus. Colocalizes with mitotic spindle. Is expressed in several structures, including embryonic/larval midgut primordium; ganglia; gut section; head epidermis primordium; and mesoderm. Human ortholog(s) of this gene implicated in type 1 diabetes mellitus. Orthologous to human RAN (RAN, member RAS oncogene family). [provided by Alliance of Genome Resources, Nov 2024]

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Species Gene Architecture aa