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RpS15Aa Ribosomal protein S15Aa [ Drosophila melanogaster (fruit fly) ]

Gene ID: 44150, updated on 4-Jan-2025

Summary

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Official Symbol
RpS15Aaprovided by FlyBase
Official Full Name
Ribosomal protein S15Aaprovided by FlyBase
Primary source
FLYBASE:FBgn0010198
Locus tag
Dmel_CG2033
See related
AllianceGenome:FB:FBgn0010198
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
anon-EST:Posey44; CG2033; Dmel\CG2033; Rp S15 Aa; RpS15a; RpS15A; S15; S15Aa; S8
Summary
A structural constituent of ribosome. Predicted to be involved in cytoplasmic translation. Located in cytosolic ribosome. Is expressed in adult head; adult heart; and organism. Used to study intrinsic cardiomyopathy. Human ortholog(s) of this gene implicated in Diamond-Blackfan anemia 20. Orthologous to human RPS15A (ribosomal protein S15a). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
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Genomic context

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See RpS15Aa in Genome Data Viewer
Location:
11E11-11E12; 1-42 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (13335637..13337705, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (13229670..13231738, complement)

Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene Peroxiredoxin 2 Neighboring gene long non-coding RNA:CR32636 Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR45708

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Suppression of a temperature-sensitive cdc33 mutation of yeast by a multicopy plasmid expressing a Drosophila ribosomal protein. Lavoie C, et al. J Biol Chem, 1994 May 20. PMID 8182070
  2. Attenuated Codon Optimality Contributes to Neural-Specific mRNA Decay in Drosophila. Burow DA, et al. Cell Rep, 2018 Aug 14. PMID 30110627, Free PMC Article
  3. How the fly balances its ability to combat different pathogens. Chambers MC, et al. PLoS Pathog, 2012. PMID 23271964, Free PMC Article
  4. Ribosome heterogeneity in Drosophila melanogaster gonads through paralog-switching. Hopes T, et al. Nucleic Acids Res, 2022 Feb 28. PMID 34283226, Free PMC Article
  5. Model system identification of novel congenital heart disease gene candidates: focus on RPL13. Schroeder AM, et al. Hum Mol Genet, 2019 Dec 1. PMID 31625562, Free PMC Article

See all (62) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables structural constituent of ribosome HDA PubMed 
enables structural constituent of ribosome IBA
Inferred from Biological aspect of Ancestor
more info
  
enables structural constituent of ribosome IDA
Inferred from Direct Assay
more info
 PubMed 
enables structural constituent of ribosome IEA
Inferred from Electronic Annotation
more info
  
enables structural constituent of ribosome TAS
Traceable Author Statement
more info
 PubMed 
Process Evidence Code Pubs
involved_in cytoplasmic translation IC
Inferred by Curator
more info
 PubMed 
involved_in cytoplasmic translation TAS
Traceable Author Statement
more info
 PubMed 
involved_in translation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytosolic ribosome HDA PubMed 
located_in cytosolic ribosome IDA
Inferred from Direct Assay
more info
 PubMed 
part_of cytosolic small ribosomal subunit IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of cytosolic small ribosomal subunit TAS
Traceable Author Statement
more info
 PubMed 
located_in ribosome IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
ribosomal protein S15Aa
Names
CG2033-PA
CG2033-PC
CG2033-PD
CG2033-PE
CG2033-PF
RpS15Aa-PA
RpS15Aa-PC
RpS15Aa-PD
RpS15Aa-PE
RpS15Aa-PF
ribosomal protein S15A

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004354.4 Reference assembly

    Range
    13335637..13337705 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_079970.6 → NP_524709.1  ribosomal protein S15Aa, isoform D [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_524709.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A4V4D9, P48149, Q9VYE4
    UniProtKB/TrEMBL
    E1JJM9
    Related
    FBpp0073625
    Conserved Domains (1) summary
    PTZ00158
    Location:1 → 130
    PTZ00158; 40S ribosomal protein S15A; Provisional

  2. NM_167362.3 → NP_727692.1  ribosomal protein S15Aa, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_727692.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A4V4D9, P48149, Q9VYE4
    UniProtKB/TrEMBL
    E1JJM9
    Related
    FBpp0073623
    Conserved Domains (1) summary
    PTZ00158
    Location:1 → 130
    PTZ00158; 40S ribosomal protein S15A; Provisional

  3. NM_001169267.2 → NP_001162738.1  ribosomal protein S15Aa, isoform F [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001162738.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A4V4D9, P48149, Q9VYE4
    UniProtKB/TrEMBL
    E1JJM9
    Conserved Domains (1) summary
    PTZ00158
    Location:1 → 130
    PTZ00158; 40S ribosomal protein S15A; Provisional

  4. NM_167360.3 → NP_727690.1  ribosomal protein S15Aa, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_727690.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A4V4D9, P48149, Q9VYE4
    UniProtKB/TrEMBL
    E1JJM9
    Related
    FBpp0073624
    Conserved Domains (1) summary
    PTZ00158
    Location:1 → 130
    PTZ00158; 40S ribosomal protein S15A; Provisional

  5. NM_167363.3 → NP_727693.1  ribosomal protein S15Aa, isoform E [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_727693.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A4V4D9, P48149, Q9VYE4
    UniProtKB/TrEMBL
    E1JJM9
    Related
    FBpp0073626
    Conserved Domains (1) summary
    PTZ00158
    Location:1 → 130
    PTZ00158; 40S ribosomal protein S15A; Provisional
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
E1JJM9 E1JJM9
P48149.2 P48149

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