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CG10939 - uncharacterized protein

Enables molecular adaptor activity. Involved in several processes, including epithelial structure maintenance; positive regulation of cell-cell adhesion; and regulation of renal system process. Is active in cytoplasmic side of apical plasma membrane. Is expressed in several structures, including adult head; anlage in statu nascendi; embryonic/larval midgut primordium; gut section; and head epidermis primordium. Used to study hypophosphatemic nephrolithiasis/osteoporosis 2. Human ortholog(s) of this gene implicated in hypophosphatemic nephrolithiasis/osteoporosis 2. Orthologous to human NHERF1 (NHERF family PDZ scaffold protein 1) and NHERF2 (NHERF family PDZ scaffold protein 2). [provided by Alliance of Genome Resources, Dec 2024]

Genes similar to CG10939

NCBI Orthologs

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Species Gene Architecture aa