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disp dispatched [ Drosophila melanogaster (fruit fly) ]

Gene ID: 44274, updated on 9-Dec-2024

Summary

Official Symbol
dispprovided by FlyBase
Official Full Name
dispatchedprovided by FlyBase
Primary source
FLYBASE:FBgn0029088
Locus tag
Dmel_CG2019
See related
AllianceGenome:FB:FBgn0029088
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
anon-WO0146227.1; CG2019; Disp; Dmel\CG2019
Summary
Involved in germ cell migration; patched ligand maturation; and regionalization. Located in cytoneme. Is expressed in adult head; imaginal disc; organism; and wing disc. Orthologous to human DISP1 (dispatched RND transporter family member 1) and DISP2 (dispatched RND transporter family member 2). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

See disp in Genome Data Viewer
Location:
83C5-83C5; 3-47.5 cM
Exon count:
7
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (5849697..5856311, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (1675419..1682033, complement)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene pseudo Neighboring gene uncharacterized protein Neighboring gene antisense RNA:CR46133 Neighboring gene ECSIT Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

mobile_element

  • Loc: c5852013-5851958 mobile_element_type = transposon:FB{}5719

Gene Ontology Provided by FlyBase

Process Evidence Code Pubs
involved_in germ cell migration IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in patched ligand maturation IDA
Inferred from Direct Assay
more info
PubMed 
involved_in patched ligand maturation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in segment polarity determination IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in smoothened signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in wing disc pattern formation IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
located_in cytoneme IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in membrane NAS
Non-traceable Author Statement
more info
PubMed 

General protein information

Preferred Names
dispatched
Names
CG2019-PA
disp-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    5849697..5856311 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_079995.3NP_524734.2  dispatched [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_524734.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    B6IDI9, Q5U173, Q8SY40, Q9U477, Q9VNJ5
    Related
    FBpp0078314
    Conserved Domains (3) summary
    pfam02460
    Location:4441111
    Patched; Patched family
    cl00454
    Location:9641109
    TM_PBP1_branched-chain-AA_like; Transmembrane subunit (TM) of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which are involved in the uptake of branched-chain amino acids (AAs), as well as TMs of transporters involved in the uptake of ...
    cl21543
    Location:457627
    MMPL; MMPL family