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Sr-CIII Scavenger receptor class C, type III [ Drosophila melanogaster (fruit fly) ]

Gene ID: 44382, updated on 9-Dec-2024

Summary

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Official Symbol
Sr-CIIIprovided by FlyBase
Official Full Name
Scavenger receptor class C, type IIIprovided by FlyBase
Primary source
FLYBASE:FBgn0020376
Locus tag
Dmel_CG31962
See related
AllianceGenome:FB:FBgn0020376
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG31962; Dmel\CG31962; dSR-CIII; SR-CIII
Summary
Predicted to be involved in nervous system development. Predicted to be located in membrane. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See Sr-CIII in Genome Data Viewer
Location:
24D6-24D6; 2-11 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (4120343..4121627)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (4120343..4121627)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene echinoid Neighboring gene antisense RNA:CR44984 Neighboring gene Scavenger receptor class C, type I Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Expression cloning of dSR-CI, a class C macrophage-specific scavenger receptor from Drosophila melanogaster. Pearson A, et al. Proc Natl Acad Sci U S A, 1995 Apr 25. PMID 7732030, Free PMC Article
  2. Linkage disequilibrium and recent selection at three immunity receptor loci in Drosophila simulans. Schlenke TA, et al. Genetics, 2005 Apr. PMID 15654108, Free PMC Article
  3. Elevated polymorphism and divergence in the class C scavenger receptors of Drosophila melanogaster and D. simulans. Lazzaro BP. Genetics, 2005 Apr. PMID 15716507, Free PMC Article
  4. New genes in Drosophila quickly become essential. Chen S, et al. Science, 2010 Dec 17. PMID 21164016, Free PMC Article
  5. Genetic basis of natural variation in D. melanogaster antibacterial immunity. Lazzaro BP, et al. Science, 2004 Mar 19. PMID 15031506

See all (33) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Hmu, Sr-CI/Sr-CIII, and Tehao have polymorphic sites in nearly perfect linkage disequilibrium
    Title: Linkage disequilibrium and recent selection at three immunity receptor loci in Drosophila simulans.
Submit: New GeneRIF Correction

General gene information

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Markers

Homology

Gene Ontology Provided by FlyBase

Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
scavenger receptor class C, type III
Names
CG31962-PA
Sr-CIII-PA
scavenger receptor

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    4120343..4121627
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_080008.2 → NP_524747.1  scavenger receptor class C, type III [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_524747.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q5ELU7, Q9N2Q3
    Related
    FBpp0077155
    Conserved Domains (3) summary
    cd06263
    Location:143 → 310
    MAM; Meprin, A5 protein, and protein tyrosine phosphatase Mu (MAM) domain. MAM is an extracellular domain which mediates protein-protein interactions and is found in a diverse set of proteins, many of which are known to function in cell adhesion. Members ...
    cd00033
    Location:27 → 62
    CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system
    pfam00629
    Location:143 → 310
    MAM; MAM domain, meprin/A5/mu
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q5ELR6 Q5ELR6
Q5ELS0 Q5ELS0
Q5ELS2 Q5ELS2
Q5ELS4 Q5ELS4
Q5ELS6 Q5ELS6
Q5ELS9 Q5ELS9
Q5ELT1 Q5ELT1
Q5ELU3 Q5ELU3
Q5ELU7 Q5ELU7
Q5ELU9 Q5ELU9
Q9N2Q3 Q9N2Q3

Gene LinkOut

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