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Spn43Aa - Serpin 43Aa

Predicted to enable serine-type endopeptidase inhibitor activity. Predicted to be involved in negative regulation of proteolysis. Located in cytoplasm. Is expressed in several structures, including clypeo-labral primordium; dorsal epidermis primordium; embryonic salivary gland duct; epithelium; and salivary gland common duct primordium. Human ortholog(s) of this gene implicated in several diseases, including autosomal recessive nonsyndromic deafness 91; intermediate coronary syndrome; neurodegenerative disease (multiple); thrombophilia (multiple); and toxic shock syndrome. Orthologous to several human genes including SERPINA12 (serpin family A member 12); SERPINB1 (serpin family B member 1); and SERPINB6 (serpin family B member 6). [provided by Alliance of Genome Resources, Dec 2024]

Genes similar to Spn43Aa

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Species Gene Architecture aa