cathD - cathepsin D

Predicted to enable aspartic-type endopeptidase activity. Involved in defense response to Gram-negative bacterium and nurse cell apoptotic process. Located in lysosome. Is expressed in several structures, including adult head; adult heart; antennal anlage; epithelium; and head epidermis primordium. Used to study neuronal ceroid lipofuscinosis. Human ortholog(s) of this gene implicated in Alzheimer's disease; breast cancer; and neuronal ceroid lipofuscinosis 10. Orthologous to human CTSD (cathepsin D). [provided by Alliance of Genome Resources, Dec 2024]

NCBI Orthologs

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