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fz - frizzled

Enables Wnt receptor activity and Wnt-protein binding activity. Involved in several processes, including neuron differentiation; positive regulation of cell projection organization; and regionalization. Located in plasma membrane. Colocalizes with endosome. Is expressed in several structures, including central nervous system; cuboidal/columnar epithelium; imaginal disc; nephrocyte; and organism subdivision. Human ortholog(s) of this gene implicated in omodysplasia 2. Orthologous to several human genes including FZD1 (frizzled class receptor 1) and FZD7 (frizzled class receptor 7). [provided by Alliance of Genome Resources, Nov 2024]

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Species Gene Architecture aa