trol - terribly reduced optic lobes

Involved in several processes, including axon development; maintenance of epithelial cell apical/basal polarity; and regulation of signal transduction. Located in basement membrane. Is expressed in several structures, including brain; embryonic/larval lymph gland; gut section; lineage NB3-1 primary motor neurons; and neuron projection bundle. Human ortholog(s) of this gene implicated in Schwartz-Jampel syndrome 1; Silverman-Handmaker type dyssegmental dysplasia; and osteochondrodysplasia. Orthologous to human HSPG2 (heparan sulfate proteoglycan 2). [provided by Alliance of Genome Resources, Dec 2024]

NCBI Orthologs

How was this calculated?