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sinu sinuous [ Drosophila melanogaster (fruit fly) ]

Gene ID: 46187, updated on 9-Dec-2024

Summary

Official Symbol
sinuprovided by FlyBase
Official Full Name
sinuousprovided by FlyBase
Primary source
FLYBASE:FBgn0010894
Locus tag
Dmel_CG10624
See related
AllianceGenome:FB:FBgn0010894
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
6524; CG10624; Dmel\CG10624; i8; l(3)06524; Sinu
Summary
Involved in several processes, including cell adhesion involved in heart morphogenesis; establishment of glial blood-brain barrier; and septate junction assembly. Located in plasma membrane and septate junction. Is expressed in several structures, including adult head; dorsal epidermis primordium; embryonic dorsal epidermis; embryonic head epidermis; and gut section. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

See sinu in Genome Data Viewer
Location:
64D3-64D3; 3-14 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (5559470..5561598, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (5552570..5554698, complement)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene farmer Neighboring gene Succinyl-coenzyme A synthetase beta subunit, GDP-forming Neighboring gene severas

Genomic regions, transcripts, and products

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General protein information

Preferred Names
sinuous
Names
CG10624-PA
sinu-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    5559470..5561598 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_139714.4NP_647971.3  sinuous [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_647971.3

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q6TDU6, Q8T047, Q9VRM3
    Conserved Domains (1) summary
    pfam13903
    Location:44223
    Claudin_2; PMP-22/EMP/MP20/Claudin tight junction