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Fkbp59 - FK506-binding protein 59kD

Predicted to enable FK506 binding activity and peptidyl-prolyl cis-trans isomerase activity. Involved in detection of light stimulus involved in visual perception and regulation of calcium ion transport. Part of inaD signaling complex. Is expressed in several structures, including adult head; embryonic/larval crystal cell; embryonic/larval garland cell; embryonic/larval midgut; and embryonic/larval midgut primordium. Human ortholog(s) of this gene implicated in alcohol dependence; heroin dependence; and major depressive disorder. Orthologous to human FKBP4 (FKBP prolyl isomerase 4) and FKBP5 (FKBP prolyl isomerase 5). [provided by Alliance of Genome Resources, Dec 2024]

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Species Gene Architecture aa