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fs(1)K10 female sterile (1) K10 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 47781, updated on 4-Jan-2025

Summary

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Official Symbol
fs(1)K10provided by FlyBase
Official Full Name
female sterile (1) K10provided by FlyBase
Primary source
FLYBASE:FBgn0000810
Locus tag
Dmel_CG3218
See related
AllianceGenome:FB:FBgn0000810
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG3218; Dmel\CG3218; EG:30B8.5; f(s)K10; fs(1)k10; fs(1)M9; K-10; k10; K10
Summary
Predicted to enable DNA binding activity. Involved in follicle cell of egg chamber development and pole plasm mRNA localization. Located in nucleus. Is expressed in several structures, including egg chamber; female germline cell; germarium; and ovary. [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
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Genomic context

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See fs(1)K10 in Genome Data Viewer
Location:
2F1-2F2; 1-0.9 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (2242138..2246041)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (2136171..2140074)

Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene pecanex Neighboring gene kurz Neighboring gene Odorant receptor 2a Neighboring gene crooked neck

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The development and function of the female germ line in Drosophila melanogaster: a cell lineage study. Wieschaus E, et al. Dev Biol, 1979 Jan. PMID 108155
  2. Role of the oocyte nucleus in determination of the dorsoventral polarity of Drosophila as revealed by molecular analysis of the K10 gene. Prost E, et al. Genes Dev, 1988 Jul. PMID 12553295
  3. A small predicted stem-loop structure mediates oocyte localization of Drosophila K10 mRNA. Serano TL, et al. Development, 1995 Nov. PMID 8582290
  4. Solution structure of the DNA binding octapeptide repeat of the K10 gene product. Suzuki M, et al. Protein Eng, 1994 Apr. PMID 8029203
  5. fs(1)K10, a germline-dependent female sterile mutation causing abnormal chorion morphology inDrosophila melanogaster. Wieschaus E, et al. Wilehm Roux Arch Dev Biol, 1978 Mar. PMID 28305014

See all (179) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables DNA binding ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Process Evidence Code Pubs
involved_in dorsal/ventral pattern formation TAS
Traceable Author Statement
more info
 PubMed 
involved_in follicle cell of egg chamber development IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in intracellular mRNA localization TAS
Traceable Author Statement
more info
 PubMed 
involved_in negative regulation of translation TAS
Traceable Author Statement
more info
 PubMed 
involved_in oogenesis IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in pole plasm mRNA localization IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in protein localization TAS
Traceable Author Statement
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleus TAS
Traceable Author Statement
more info
 PubMed 

General protein information

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Preferred Names
female sterile (1) K10
Names
CG3218-PA
fs(1)K10-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004354.4 Reference assembly

    Range
    2242138..2246041
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_058143.4 → NP_477491.1  female sterile (1) K10 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_477491.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O46075, P13468, Q9W505
    Related
    FBpp0070380
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P13468.2 P13468

Gene LinkOut

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