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TCAF2 TRPM8 channel associated factor 2 [ Canis lupus familiaris (dog) ]

Gene ID: 482731, updated on 5-Mar-2024

Summary

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Gene symbol
TCAF2
Gene description
TRPM8 channel associated factor 2
See related
Ensembl:ENSCAFG00845013593
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Also known as
FAM115C
Orthologs
human mouse all
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Genomic context

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See TCAF2 in Genome Data Viewer
Location:
chromosome: 16
Exon count:
10
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 16 NC_051820.1 (5961988..5986095)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 16 NC_006598.4 (7097329..7121443)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 16 NC_049237.1 (5836684..5860797)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 16 NC_049276.1 (5909927..5934145)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 16 NC_049757.1 (5760372..5784463)

Chromosome 16 - NC_051820.1Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 2 subfamily F member 2 Neighboring gene TRPM8 channel associated factor 1 Neighboring gene uncharacterized LOC102155280 Neighboring gene methylosome subunit pICln-like Neighboring gene olfactory receptor family 10 subfamily AC member 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. TRP channel-associated factors are a novel protein family that regulates TRPM8 trafficking and activity. Gkika D, et al. J Cell Biol, 2015 Jan 5. PMID 25559186, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Process Evidence Code Pubs
involved_in negative regulation of anion channel activity IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
TRPM8 channel-associated factor 2
Names
family with sequence similarity 115, member C

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051820.1 Reference ROS_Cfam_1.0

    Range
    5961988..5986095
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038689001.1 → XP_038544929.1  TRPM8 channel-associated factor 2 isoform X1

    UniProtKB/TrEMBL
    A0A8C0L920, A0A8C0MK87, A0A8I3P0A6
    Related
    ENSCAFP00845019033.1, ENSCAFT00845024227.1
    Conserved Domains (2) summary
    pfam13402
    Location:634 → 889
    Peptidase_M60; Peptidase M60, enhancin and enhancin-like
    pfam17291
    Location:524 → 631
    M60-like_N; N-terminal domain of M60-like peptidases

  2. XM_038689003.1 → XP_038544931.1  TRPM8 channel-associated factor 2 isoform X2

    UniProtKB/TrEMBL
    A0A8C0L920, A0A8C0REE6
    Conserved Domains (2) summary
    pfam13402
    Location:634 → 842
    Peptidase_M60; Peptidase M60, enhancin and enhancin-like
    pfam17291
    Location:524 → 631
    M60-like_N; N-terminal domain of M60-like peptidases

  3. XM_038689002.1 → XP_038544930.1  TRPM8 channel-associated factor 2 isoform X1

    UniProtKB/TrEMBL
    A0A8C0L920, A0A8C0MK87, A0A8I3P0A6
    Conserved Domains (2) summary
    pfam13402
    Location:634 → 889
    Peptidase_M60; Peptidase M60, enhancin and enhancin-like
    pfam17291
    Location:524 → 631
    M60-like_N; N-terminal domain of M60-like peptidases

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049276.1 Alternate UMICH_Zoey_3.1

    Range
    5909927..5934145
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038496954.1 → XP_038352882.1  TRPM8 channel-associated factor 2 isoform X1

    Conserved Domains (2) summary
    pfam13402
    Location:634 → 889
    Peptidase_M60; Peptidase M60, enhancin and enhancin-like
    pfam17291
    Location:524 → 631
    M60-like_N; N-terminal domain of M60-like peptidases

  2. XM_038496956.1 → XP_038352884.1  TRPM8 channel-associated factor 2 isoform X2

    Conserved Domains (2) summary
    pfam13402
    Location:634 → 842
    Peptidase_M60; Peptidase M60, enhancin and enhancin-like
    pfam17291
    Location:524 → 631
    M60-like_N; N-terminal domain of M60-like peptidases

  3. XM_038496955.1 → XP_038352883.1  TRPM8 channel-associated factor 2 isoform X1

    Conserved Domains (2) summary
    pfam13402
    Location:634 → 889
    Peptidase_M60; Peptidase M60, enhancin and enhancin-like
    pfam17291
    Location:524 → 631
    M60-like_N; N-terminal domain of M60-like peptidases

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049757.1 Alternate UNSW_CanFamBas_1.0

    Range
    5760372..5784463
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038623267.1 → XP_038479195.1  TRPM8 channel-associated factor 2 isoform X1

  2. XM_038623270.1 → XP_038479198.1  TRPM8 channel-associated factor 2 isoform X2

  3. XM_038623268.1 → XP_038479196.1  TRPM8 channel-associated factor 2 isoform X1

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049237.1 Alternate UU_Cfam_GSD_1.0

    Range
    5836684..5860797
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038559286.1 → XP_038415214.1  TRPM8 channel-associated factor 2 isoform X1

    UniProtKB/TrEMBL
    A0A8C0L920

  2. XM_038559289.1 → XP_038415217.1  TRPM8 channel-associated factor 2 isoform X2

    UniProtKB/TrEMBL
    A0A8C0L920

  3. XM_038559288.1 → XP_038415216.1  TRPM8 channel-associated factor 2 isoform X1

    UniProtKB/TrEMBL
    A0A8C0L920

  4. XM_038559287.1 → XP_038415215.1  TRPM8 channel-associated factor 2 isoform X1

    UniProtKB/TrEMBL
    A0A8C0L920

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006598.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    7097329..7121443
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038452296.1 → XP_038308224.1  TRPM8 channel-associated factor 2 isoform X1

    UniProtKB/TrEMBL
    A0A8C0L920, A0A8C0Q8R1, A0A8P0N6F2
    Conserved Domains (2) summary
    pfam13402
    Location:634 → 889
    Peptidase_M60; Peptidase M60, enhancin and enhancin-like
    pfam17291
    Location:524 → 631
    M60-like_N; N-terminal domain of M60-like peptidases

  2. XM_038452298.1 → XP_038308226.1  TRPM8 channel-associated factor 2 isoform X2

    UniProtKB/TrEMBL
    A0A8C0L920
    Conserved Domains (2) summary
    pfam13402
    Location:634 → 842
    Peptidase_M60; Peptidase M60, enhancin and enhancin-like
    pfam17291
    Location:524 → 631
    M60-like_N; N-terminal domain of M60-like peptidases

  3. XM_038452297.1 → XP_038308225.1  TRPM8 channel-associated factor 2 isoform X1

    UniProtKB/TrEMBL
    A0A8C0L920, A0A8C0Q8R1, A0A8P0N6F2
    Conserved Domains (2) summary
    pfam13402
    Location:634 → 889
    Peptidase_M60; Peptidase M60, enhancin and enhancin-like
    pfam17291
    Location:524 → 631
    M60-like_N; N-terminal domain of M60-like peptidases
Nucleotide Protein
Heading Accession and Version

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