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Kebab Kinetochore and EB1 associated basic protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 48440, updated on 9-Dec-2024

Summary

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Official Symbol
Kebabprovided by FlyBase
Official Full Name
Kinetochore and EB1 associated basic proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0028952
Locus tag
Dmel_CG31672
See related
AllianceGenome:FB:FBgn0028952
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
BEST:LD15963; CG31672; CG4248; Dmel\CG31672; keb; kebab; n(2)k09932
Summary
Enables kinetochore binding activity and microtubule binding activity. Located in kinetochore; perinuclear region of cytoplasm; and spindle microtubule. Is expressed in organism. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See Kebab in Genome Data Viewer
Location:
22C1-22C1; 2-4 cM
Exon count:
4
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (2045494..2048054)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (2045494..2048054)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR45298 Neighboring gene Suppressor of deltex Neighboring gene Odorant receptor 22c Neighboring gene defective proboscis extension response 3 Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Kebab: kinetochore and EB1 associated basic protein that dynamically changes its localisation during Drosophila mitosis. Meireles AM, et al. PLoS One, 2011. PMID 21912673, Free PMC Article
  2. The exon junction complex differentially marks spliced junctions. Saulière J, et al. Nat Struct Mol Biol, 2010 Oct. PMID 20818392
  3. Slowed aging during reproductive dormancy is reflected in genome-wide transcriptome changes in Drosophila melanogaster. Kučerová L, et al. BMC Genomics, 2016 Jan 13. PMID 26758761, Free PMC Article
  4. Landscape of protein-protein interactions in Drosophila immune deficiency signaling during bacterial challenge. Fukuyama H, et al. Proc Natl Acad Sci U S A, 2013 Jun 25. PMID 23749869, Free PMC Article
  5. The Berkeley Drosophila Genome Project gene disruption project: Single P-element insertions mutating 25% of vital Drosophila genes. Spradling AC, et al. Genetics, 1999 Sep. PMID 10471706, Free PMC Article

See all (24) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. the identification of a novel Drosophila protein
    Title: Kebab: kinetochore and EB1 associated basic protein that dynamically changes its localisation during Drosophila mitosis.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables kinetochore binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables microtubule binding IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
located_in kinetochore IDA
Inferred from Direct Assay
more info
 PubMed 
located_in perinuclear region of cytoplasm IDA
Inferred from Direct Assay
more info
 PubMed 
located_in spindle microtubule IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
kinetochore and EB1 associated basic protein
Names
CG31672-PA
CG31672-PB
Kebab-PA
Kebab-PB

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    2045494..2048054
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_164451.2 → NP_722756.1  kinetochore and EB1 associated basic protein, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_722756.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    F0JAI6
    Related
    FBpp0077498
    Conserved Domains (1) summary
    pfam11725
    Location:77 → 307
    AvrE; Pathogenicity factor

  2. NM_001272971.1 → NP_001259900.1  kinetochore and EB1 associated basic protein, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001259900.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    F0JAI6, Q961C7, Q9VQ69
    Conserved Domains (1) summary
    pfam11725
    Location:77 → 308
    AvrE; Pathogenicity factor
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
F0JAI6.1 F0JAI6

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