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BomS2 Bomanin Short 2 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 49802, updated on 9-Dec-2024

Summary

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Official Symbol
BomS2provided by FlyBase
Official Full Name
Bomanin Short 2provided by FlyBase
Primary source
FLYBASE:FBgn0025583
Locus tag
Dmel_CG18106
See related
AllianceGenome:FB:FBgn0025583
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
anon-WO0140519.2; BcDNA:RH08291; Bom2; bomS2; CG18106; DIM 2; DIM-2; DIM2; Dmel\CG18106; Im2; IM2
Summary
Involved in defense response. Located in extracellular region. Is expressed in larval central nervous system. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See BomS2 in Genome Data Viewer
Location:
55C4-55C4; 2-85 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (18386602..18387030)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (14274107..14274535)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene Bomanin Short 1 Neighboring gene Bomanin Short 4 Neighboring gene Bomanin Bicipital 2 Neighboring gene Bomanin Short 3 Neighboring gene Bomanin Tailed 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The genetic basis of variation in immune defense against Lysinibacillus fusiformis infection in Drosophila melanogaster. Smith BR, et al. PLoS Pathog, 2023 Aug. PMID 37549163, Free PMC Article
  2. Inhibition of NF-κB in astrocytes is sufficient to delay neurodegeneration induced by proteotoxicity in neurons. Li YX, et al. J Neuroinflammation, 2018 Sep 11. PMID 30205834, Free PMC Article
  3. LncRNA-CR11538 Decoys Dif/Dorsal to Reduce Antimicrobial Peptide Products for Restoring Drosophila Toll Immunity Homeostasis. Zhou H, et al. Int J Mol Sci, 2021 Sep 18. PMID 34576280, Free PMC Article
  4. A Toll pathway effector protects Drosophila specifically from distinct toxins secreted by a fungus or a bacterium. Huang J, et al. Proc Natl Acad Sci U S A, 2023 Mar 21. PMID 36917667, Free PMC Article
  5. Specific calcineurin isoforms are involved in Drosophila toll immune signaling. Li YX, et al. J Immunol, 2015 Jan 1. PMID 25429067

See all (104) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Process Evidence Code Pubs
involved_in defense response IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in defense response IEA
Inferred from Electronic Annotation
more info
  
involved_in defense response NAS
Non-traceable Author Statement
more info
 PubMed 
involved_in response to bacterium HEP PubMed 
Component Evidence Code Pubs
located_in extracellular region IDA
Inferred from Direct Assay
more info
 PubMed 
located_in extracellular region NAS
Non-traceable Author Statement
more info
 PubMed 

General protein information

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Preferred Names
bomanin short 2
Names
BomS2-PA
CG18106-PA
Immune-induced molecule 2
Immune-induced peptide 2 precursor
bomanin 2
bomanin S2
immune induced molecule 2
immune induced peptide 2
immune molecule 2

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    18386602..18387030
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_166277.3 → NP_725776.1  bomanin short 2 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_725776.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O77150, Q8MLI5, Q9V8F9
    Related
    FBpp0085845
    Conserved Domains (1) summary
    pfam08194
    Location:13 → 40
    DIM; DIM protein
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
O77150.2 O77150

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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