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Spn38F - Serpin 38F

Predicted to enable serine-type endopeptidase inhibitor activity. Involved in defense response to Gram-negative bacterium. Located in extracellular space. Is expressed in several structures, including adult head; adult hemolymph; female reproductive system; oviduct; and sperm storage organ. Human ortholog(s) of this gene implicated in several diseases, including IgA glomerulonephritis; Nagashima-type palmoplantar keratosis; autosomal recessive nonsyndromic deafness 91; familial encephalopathy with neuroserpin inclusion bodies; and thrombophilia (multiple). Orthologous to several human genes including SERPINB1 (serpin family B member 1); SERPINB12 (serpin family B member 12); and SERPINB13 (serpin family B member 13). [provided by Alliance of Genome Resources, Dec 2024]

NCBI Orthologs

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Species Gene Architecture aa