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GCS2alpha - Glucosidase 2 alpha subunit

Predicted to enable glucan 1,3-alpha-glucosidase activity. Predicted to be involved in N-glycan processing. Located in endomembrane system and extracellular region. Is expressed in several structures, including adult head; adult heart; anterior endoderm; gut section; and mesoderm. Human ortholog(s) of this gene implicated in polycystic kidney disease; polycystic kidney disease 3; and polycystic liver disease. Orthologous to several human genes including GANAB (glucosidase II alpha subunit). [provided by Alliance of Genome Resources, Nov 2024]

NCBI Orthologs

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Species Gene Architecture aa