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Ppp1r1c protein phosphatase 1, regulatory (inhibitor) subunit 1C [ Rattus norvegicus (Norway rat) ]

Gene ID: 499818, updated on 27-Nov-2024

Summary

Official Symbol
Ppp1r1cprovided by RGD
Official Full Name
protein phosphatase 1, regulatory (inhibitor) subunit 1Cprovided by RGD
Primary source
RGD:1562095
See related
EnsemblRapid:ENSRNOG00000024990 AllianceGenome:RGD:1562095
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1562095
Summary
Predicted to enable protein phosphatase inhibitor activity. Predicted to be involved in intracellular signal transduction. Predicted to be active in cytoplasm. Orthologous to human PPP1R1C (protein phosphatase 1 regulatory inhibitor subunit 1C). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Thymus (RPKM 17.4), Muscle (RPKM 3.2) and 1 other tissue See more
Orthologs
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Genomic context

See Ppp1r1c in Genome Data Viewer
Location:
3q24
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 3 NC_086021.1 (85023621..85126609)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 3 NC_051338.1 (64616700..64719696)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (66673060..66783501)

Chromosome 3 - NC_086021.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC103691830 Neighboring gene ITPR interacting domain containing 2 Neighboring gene phosphodiesterase 1A Neighboring gene uncharacterized LOC134486399 Neighboring gene uncharacterized LOC103691836

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Markers

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables protein phosphatase inhibitor activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in intracellular signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
protein phosphatase 1 regulatory subunit 1C

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001109200.2NP_001102670.1  protein phosphatase 1 regulatory subunit 1C

    See identical proteins and their annotated locations for NP_001102670.1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000003
    UniProtKB/TrEMBL
    A6HML7, D3ZSW2
    Related
    ENSRNOP00000035714.3, ENSRNOT00000034769.6
    Conserved Domains (1) summary
    pfam05395
    Location:284
    DARPP-32; Protein phosphatase inhibitor 1/DARPP-32

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086021.1 Reference GRCr8

    Range
    85023621..85126609
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)