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Depp1 DEPP autophagy regulator 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 500300, updated on 2-Nov-2024

Summary

Official Symbol
Depp1provided by RGD
Official Full Name
DEPP autophagy regulator 1provided by RGD
Primary source
RGD:1565700
See related
EnsemblRapid:ENSRNOG00000023465 AllianceGenome:RGD:1565700
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Depp
Summary
Predicted to be involved in regulation of autophagy. Predicted to be located in peroxisome. Predicted to be active in mitochondrion. Orthologous to human DEPP1 (DEPP autophagy regulator 1). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Heart (RPKM 189.7), Liver (RPKM 101.1) and 6 other tissues See more
Orthologs
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Genomic context

See Depp1 in Genome Data Viewer
Location:
4q42
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 4 NC_086022.1 (151583105..151585455)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 4 NC_051339.1 (149910794..149913013)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (148780330..148784566)

Chromosome 4 - NC_086022.1Genomic Context describing neighboring genes Neighboring gene transfer RNA cysteine (anticodon GCA) 29 Neighboring gene zinc finger protein 422 Neighboring gene Ras association domain family member 4 Neighboring gene transmembrane protein 72 Neighboring gene small nucleolar RNA SNORA17

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Markers

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in regulation of autophagy IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in regulation of autophagy IEA
Inferred from Electronic Annotation
more info
 
involved_in regulation of autophagy ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in intracellular membrane-bounded organelle ISO
Inferred from Sequence Orthology
more info
 
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 
located_in mitochondrion ISO
Inferred from Sequence Orthology
more info
 
located_in peroxisome IEA
Inferred from Electronic Annotation
more info
 
located_in peroxisome ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
protein DEPP
Names
DEPP1, autophagy regulator
decidual protein induced by progesterone

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001024334.2NP_001019505.2  protein DEPP

    See identical proteins and their annotated locations for NP_001019505.2

    Status: PROVISIONAL

    Source sequence(s)
    BC087112
    UniProtKB/Swiss-Prot
    Q5BMD4, Q5PQM5
    UniProtKB/TrEMBL
    A0A0G2JSM9, A6IL27
    Conserved Domains (1) summary
    pfam15343
    Location:25205
    DEPP; Decidual protein induced by progesterone family

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086022.1 Reference GRCr8

    Range
    151583105..151585455
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006237197.5XP_006237259.1  protein DEPP isoform X1

    See identical proteins and their annotated locations for XP_006237259.1

    UniProtKB/Swiss-Prot
    Q5BMD4, Q5PQM5
    UniProtKB/TrEMBL
    A0A0G2JSM9, A6IL27
    Conserved Domains (1) summary
    pfam15343
    Location:25205
    DEPP; Decidual protein induced by progesterone family
  2. XM_006237196.5XP_006237258.1  protein DEPP isoform X1

    See identical proteins and their annotated locations for XP_006237258.1

    UniProtKB/Swiss-Prot
    Q5BMD4, Q5PQM5
    UniProtKB/TrEMBL
    A0A0G2JSM9, A6IL27
    Related
    ENSRNOP00000018133.3, ENSRNOT00000018133.7
    Conserved Domains (1) summary
    pfam15343
    Location:25205
    DEPP; Decidual protein induced by progesterone family