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Gli4 GLI family zinc finger 4 [ Rattus norvegicus (Norway rat) ]

Gene ID: 500893, updated on 2-Nov-2024

Summary

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Symbol
Gli4provided by RGD
Full Name
GLI family zinc finger 4provided by RGD
Primary source
RGD:1560906
See related
EnsemblRapid:ENSRNOG00000021765 AllianceGenome:RGD:1560906
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Orthologous to human GLI4 (GLI family zinc finger 4). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Heart (RPKM 45.7), Kidney (RPKM 37.7) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Gli4 in Genome Data Viewer
Location:
7q34
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 7 NC_086025.1 (109205812..109211650)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 7 NC_051342.1 (107325584..107330911)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (116671931..116677188)

Chromosome 7 - NC_086025.1Genomic Context describing neighboring genes Neighboring gene glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1 Neighboring gene zinc finger protein 41 Neighboring gene DNA topoisomerase I mitochondrial Neighboring gene uncharacterized LOC134479926 Neighboring gene rhophilin, Rho GTPase binding protein 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC114422

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
zinc finger protein GLI4
Names
zinc finger protein GLI4-like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001029926.1 → NP_001025097.1  zinc finger protein GLI4

    See identical proteins and their annotated locations for NP_001025097.1

    Status: PROVISIONAL

    Source sequence(s)
    BC097383
    UniProtKB/TrEMBL
    Q4QR79
    Conserved Domains (3) summary
    COG5048
    Location:115 → 337
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:263 → 283
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:331 → 356
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086025.1 Reference GRCr8

    Range
    109205812..109211650
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006241856.5 → XP_006241918.1  zinc finger protein GLI4 isoform X1

    See identical proteins and their annotated locations for XP_006241918.1

    UniProtKB/TrEMBL
    Q4QR79
    Related
    ENSRNOP00000036983.3, ENSRNOT00000029711.7
    Conserved Domains (3) summary
    COG5048
    Location:115 → 337
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:263 → 283
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:331 → 356
    zf-H2C2_2; Zinc-finger double domain

  2. XM_039079757.2 → XP_038935685.1  zinc finger protein GLI4 isoform X1

    UniProtKB/TrEMBL
    Q4QR79
    Conserved Domains (3) summary
    COG5048
    Location:115 → 337
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:263 → 283
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:331 → 356
    zf-H2C2_2; Zinc-finger double domain

  3. XM_017595052.3 → XP_017450541.1  zinc finger protein GLI4 isoform X2

    UniProtKB/TrEMBL
    A0A0G2K898
    Related
    ENSRNOP00000074524.2, ENSRNOT00000077773.3

  4. XM_063264126.1 → XP_063120196.1  zinc finger protein GLI4 isoform X2

    UniProtKB/TrEMBL
    A0A0G2K898

  5. XM_063264125.1 → XP_063120195.1  zinc finger protein GLI4 isoform X1

    UniProtKB/TrEMBL
    Q4QR79

  6. XM_006241858.3 → XP_006241920.1  zinc finger protein GLI4 isoform X1

    See identical proteins and their annotated locations for XP_006241920.1

    UniProtKB/TrEMBL
    Q4QR79
    Conserved Domains (3) summary
    COG5048
    Location:115 → 337
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:263 → 283
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:331 → 356
    zf-H2C2_2; Zinc-finger double domain

  7. XM_063264127.1 → XP_063120197.1  zinc finger protein GLI4 isoform X3

Nucleotide Protein Strain
Heading Accession and Version

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