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Spase12 Spase 12-subunit [ Drosophila melanogaster (fruit fly) ]

Gene ID: 50096, updated on 9-Dec-2024

Summary

Official Symbol
Spase12provided by FlyBase
Official Full Name
Spase 12-subunitprovided by FlyBase
Primary source
FLYBASE:FBgn0040623
Locus tag
Dmel_CG11500
See related
AllianceGenome:FB:FBgn0040623
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG11500; CG31042; Dmel\CG11500; spase12
Summary
Predicted to be involved in protein targeting to ER and signal peptide processing. Predicted to be located in membrane. Predicted to be part of signal peptidase complex. Is expressed in adult head; embryonic/larval salivary gland; embryonic/larval salivary gland body; organism; and salivary gland body primordium. Orthologous to human SPCS1 (signal peptidase complex subunit 1). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

See Spase12 in Genome Data Viewer
Location:
99B1-99B1; 3-99 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (29490544..29491150, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (25316266..25316872, complement)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Protein tyrosine phosphatase 99A Neighboring gene long non-coding RNA:CR44022 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene diedel

Genomic regions, transcripts, and products

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by FlyBase

Process Evidence Code Pubs
involved_in protein targeting to ER IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in signal peptide processing IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in signal peptide processing IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
part_of signal peptidase complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of signal peptidase complex IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
spase 12-subunit
Names
CG11500-PA
Spase12-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    29490544..29491150 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_176583.3NP_788760.1  spase 12-subunit [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_788760.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9VAL0
    UniProtKB/TrEMBL
    C6SUX5
    Related
    FBpp0084801
    Conserved Domains (1) summary
    pfam06645
    Location:876
    SPC12; Microsomal signal peptidase 12 kDa subunit (SPC12)