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Rfx8 regulatory factor X8 [ Rattus norvegicus (Norway rat) ]

Gene ID: 501127, updated on 9-Dec-2024

Summary

Official Symbol
Rfx8provided by RGD
Official Full Name
regulatory factor X8provided by RGD
Primary source
RGD:1560724
See related
EnsemblRapid:ENSRNOG00000058243 AllianceGenome:RGD:1560724
Gene type
protein coding
RefSeq status
MODEL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1560724; RGD1565676
Summary
Predicted to enable DNA binding activity and DNA-binding transcription factor activity. Predicted to be involved in regulation of DNA-templated transcription. Orthologous to human RFX8 (regulatory factor X8). [provided by Alliance of Genome Resources, Dec 2024]
Expression
Biased expression in Testes (RPKM 137.5), Lung (RPKM 30.6) and 6 other tissues See more
Orthologs
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Genomic context

See Rfx8 in Genome Data Viewer
Location:
9q22
Exon count:
15
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 9 NC_086027.1 (49453282..49517123, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 9 NC_051344.1 (41957589..42021432, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 9 NC_005108.4 (46414407..46476076, complement)

Chromosome 9 - NC_086027.1Genomic Context describing neighboring genes Neighboring gene ring finger protein 149, pseudogene 2 Neighboring gene ring finger protein 149 Neighboring gene cellular repressor of E1A-stimulated genes 2 Neighboring gene uncharacterized LOC134480363 Neighboring gene small nucleolar RNA SNORA17 Neighboring gene uncharacterized LOC108351918 Neighboring gene uncharacterized LOC120094674 Neighboring gene cytochrome c oxidase subunit 6A1, pseudogene 2

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General protein information

Preferred Names
DNA-binding protein RFX8
Names
RFX family member 8, lacking RFX DNA binding domain
RFX gene family member 8, lacking RFX DNA binding domain
regulatory factor X 8

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086027.1 Reference GRCr8

    Range
    49453282..49517123 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039084547.1XP_038940475.1  DNA-binding protein RFX8 isoform X2

    UniProtKB/TrEMBL
    A0A8I6GDI7
    Related
    ENSRNOP00000110617.1, ENSRNOT00000161743.1
    Conserved Domains (1) summary
    pfam02257
    Location:1983
    RFX_DNA_binding; RFX DNA-binding domain
  2. XM_039084546.1XP_038940474.1  DNA-binding protein RFX8 isoform X1

    UniProtKB/TrEMBL
    A0A0G2K3E1, A0A8I6GDI7
    Related
    ENSRNOP00000085957.2, ENSRNOT00000108584.2
    Conserved Domains (1) summary
    pfam02257
    Location:1990
    RFX_DNA_binding; RFX DNA-binding domain