Rbm44 RNA binding motif protein 44 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Rbm44provided by RGD
Official Full Name: RNA binding motif protein 44provided by RGD
Primary source: RGD:1566074
See related: EnsemblRapid:ENSRNOG00000024878 AllianceGenome:RGD:1566074
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: RGD1566074
Summary: Predicted to enable mRNA 3'-UTR binding activity and protein homodimerization activity. Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be located in cytoplasm and intercellular bridge. Predicted to be part of catalytic step 2 spliceosome. Orthologous to human RBM44 (RNA binding motif protein 44). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Restricted expression toward (RPKM 331.4) See more
Orthologs: human mouse all
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Genomic context

Location:: 9q36

Exon count:: 16

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	9	NC_086027.1 (99178706..99204344)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	9	NC_051344.1 (91731153..91756783)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	9	NC_005108.4 (98279031..98305248)

Chromosome 9 - NC_086027.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables RNA binding	IEA Inferred from Electronic Annotation more info
enables mRNA 3'-UTR binding	IBA Inferred from Biological aspect of Ancestor more info
enables protein homodimerization activity	ISO Inferred from Sequence Orthology more info
enables protein homodimerization activity	ISS Inferred from Sequence or Structural Similarity more info

Process	Evidence Code	Pubs
involved_in mRNA splicing, via spliceosome	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
part_of catalytic step 2 spliceosome	IBA Inferred from Biological aspect of Ancestor more info
located_in cytoplasm	ISO Inferred from Sequence Orthology more info
located_in cytoplasm	ISS Inferred from Sequence or Structural Similarity more info
located_in intercellular bridge	ISO Inferred from Sequence Orthology more info
located_in intercellular bridge	ISS Inferred from Sequence or Structural Similarity more info

General protein information

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Preferred Names: RNA-binding protein 44

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001419673.1 → NP_001406602.1 RNA-binding protein 44

Status: VALIDATED

Source sequence(s)

JAXUCZ010000009

UniProtKB/Swiss-Prot

D3Z987

UniProtKB/TrEMBL

R9PXX2

Related

ENSRNOP00000034920.7, ENSRNOT00000038536.8

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

NC_086027.1 Reference GRCr8

Range

99178706..99204344

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_008767346.4 → XP_008765568.1 RNA-binding protein 44 isoform X1

See identical proteins and their annotated locations for XP_008765568.1

UniProtKB/Swiss-Prot

D3Z987

UniProtKB/TrEMBL

R9PXX2

Conserved Domains (2) summary

COG0724
Location:708 → 867

RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]

cd12248
Location:795 → 868

RRM_RBM44; RNA recognition motif in RNA-binding protein 44 (RBM44) and similar proteins