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Dso1 Daisho1 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 50126, updated on 4-Jan-2025

Summary

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Official Symbol
Dso1provided by FlyBase
Official Full Name
Daisho1provided by FlyBase
Primary source
FLYBASE:FBgn0040653
Locus tag
Dmel_CG15231
See related
AllianceGenome:FB:FBgn0040653
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
BcDNA:RH25931; CG15231; DIM 4; DIM-4; DIM4; Dmel\CG15231; dso1; IM4
Summary
Involved in antifungal humoral response. Located in extracellular space. Is expressed in embryonic/larval hemolymph and larval central nervous system. [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
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Genomic context

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See Dso1 in Genome Data Viewer
Location:
57B3-57B3; 2-92 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (20868496..20869321, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (16756001..16756826, complement)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Carbonic anhydrase 14 Neighboring gene Daisho2 Neighboring gene Inositol phosphate kinase 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The Daisho Peptides Mediate Drosophila Defense Against a Subset of Filamentous Fungi. Cohen LB, et al. Front Immunol, 2020. PMID 32038657, Free PMC Article
  2. An unusual Toll/MyD88-mediated Drosophila host defence against Talaromyces marneffei. Wang X, et al. Fly (Austin), 2024 Dec. PMID 39239739, Free PMC Article
  3. A Toll pathway effector protects Drosophila specifically from distinct toxins secreted by a fungus or a bacterium. Huang J, et al. Proc Natl Acad Sci U S A, 2023 Mar 21. PMID 36917667, Free PMC Article
  4. Hazardous effects of octopamine receptor agonists on altering metabolism-related genes and behavior of Drosophila melanogaster. Ahmed MAI, et al. Chemosphere, 2020 Aug. PMID 32283422, Free PMC Article
  5. Exploring the multilevel hazards of thiamethoxam using Drosophila melanogaster. Li X, et al. J Hazard Mater, 2020 Feb 15. PMID 31630861

See all (78) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Process Evidence Code Pubs
involved_in antifungal humoral response IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in defense response IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in defense response NAS
Non-traceable Author Statement
more info
 PubMed 
involved_in humoral immune response IEP
Inferred from Expression Pattern
more info
 PubMed 
involved_in response to bacterium HEP PubMed 
Component Evidence Code Pubs
located_in extracellular region IDA
Inferred from Direct Assay
more info
 PubMed 
located_in extracellular region NAS
Non-traceable Author Statement
more info
 PubMed 
located_in extracellular space IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
Daisho1
Names
CG15231-PA
CG15231-PB
Dso1-PA
Dso1-PB
daisho1
drosophila immune-induced molecule 4
immune induced molecule 4
immune induced peptide 4

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    20868496..20869321 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001299719.1 → NP_001286648.1  Daisho1, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001286648.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A0A0B4LG54, P82705, Q9W2Q9

  2. NM_144038.3 → NP_652295.1  Daisho1, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_652295.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A0A0B4LG54, P82705, Q9W2Q9
    Related
    FBpp0071487
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P82705.2 P82705

Gene LinkOut

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