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Slc10a3 solute carrier family 10, member 3 [ Rattus norvegicus (Norway rat) ]

Gene ID: 501665, updated on 27-Nov-2024

Summary

Official Symbol
Slc10a3provided by RGD
Official Full Name
solute carrier family 10, member 3provided by RGD
Primary source
RGD:1563513
See related
EnsemblRapid:ENSRNOG00000060580 AllianceGenome:RGD:1563513
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable bile acid:sodium symporter activity. Predicted to be involved in bile acid and bile salt transport. Predicted to act upstream of or within response to retinoic acid. Predicted to be located in membrane. Orthologous to human SLC10A3 (solute carrier family 10 member 3). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Lung (RPKM 48.6), Adrenal (RPKM 36.8) and 9 other tissues See more
Orthologs
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Genomic context

See Slc10a3 in Genome Data Viewer
Location:
Xq37
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) X NC_086039.1 (157306043..157309849, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) X NC_051356.1 (152154757..152158563, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) X NC_005120.4 (156335385..156340256)

Chromosome X - NC_086039.1Genomic Context describing neighboring genes Neighboring gene L antigen family, member 3 Neighboring gene ubiquitin-like 4A Neighboring gene FAM3 metabolism regulating signaling molecule A Neighboring gene glucose-6-phosphate dehydrogenase Neighboring gene inhibitor of nuclear factor kappa B kinase regulatory subunit gamma

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Markers

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables bile acid:sodium symporter activity IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in bile acid and bile salt transport IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within response to retinoic acid ISO
Inferred from Sequence Orthology
more info
 
involved_in sodium ion transport IEA
Inferred from Electronic Annotation
more info
 
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
P3 protein
Names
solute carrier family 10 (sodium/bile acid cotransporter family), member 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001024368.1NP_001019539.1  P3 protein

    See identical proteins and their annotated locations for NP_001019539.1

    Status: PROVISIONAL

    Source sequence(s)
    BC086556
    UniProtKB/TrEMBL
    A0A0G2K9Z0, A0A8I5ZW70, Q5RJP6
    Related
    ENSRNOP00000075188.1, ENSRNOT00000082124.3
    Conserved Domains (1) summary
    pfam01758
    Location:197376
    SBF; Sodium Bile acid symporter family

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086039.1 Reference GRCr8

    Range
    157306043..157309849 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)