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CG18675 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 50169, updated on 4-Jan-2025

Summary

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Official Symbol
CG18675provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0040696
Locus tag
Dmel_CG18675
See related
AllianceGenome:FB:FBgn0040696
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG18675
Summary
Predicted to be involved in regulation of cilium movement. Is expressed in several structures, including embryonic head sensory system; embryonic labial sensory complex; embryonic maxillary sensory complex; sensory nervous system primordium; and ventral sensory complex anlage. Human ortholog(s) of this gene implicated in primary ciliary dyskinesia 26. Orthologous to human CFAP298 (cilia and flagella associated protein 298). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
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Genomic context

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See CG18675 in Genome Data Viewer
Location:
64A9-64A10; 3-10 cM
Exon count:
4
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (4173884..4192968)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (4173884..4192968)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR44529 Neighboring gene Endoplasmic reticulum oxidoreductin-1-like Neighboring gene tipE homolog 4 Neighboring gene tipE homolog 2 Neighboring gene Vacuolar H[+] ATPase M9.7 subunit c Neighboring gene tipE homolog 3 Neighboring gene temperature-induced paralytic E Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Cuticular protein 64Aa

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A remarkably stable TipE gene cluster: evolution of insect Para sodium channel auxiliary subunits. Li J, et al. BMC Evol Biol, 2011 Nov 18. PMID 22098672, Free PMC Article
  2. Decoding cilia function: defining specialized genes required for compartmentalized cilia biogenesis. Avidor-Reiss T, et al. Cell, 2004 May 14. PMID 15137945
  3. Survey of the Ciliary Motility Machinery of Drosophila Sperm and Ciliated Mechanosensory Neurons Reveals Unexpected Cell-Type Specific Variations: A Model for Motile Ciliopathies. Zur Lage P, et al. Front Genet, 2019. PMID 30774648, Free PMC Article
  4. Identification of neural outgrowth genes using genome-wide RNAi. Sepp KJ, et al. PLoS Genet, 2008 Jul 4. PMID 18604272, Free PMC Article
  5. Global analysis of patterns of gene expression during Drosophila embryogenesis. Tomancak P, et al. Genome Biol, 2007. PMID 17645804, Free PMC Article

See all (32) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in regulation of cilium movement IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG18675-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    4173884..4192968
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_144077.3 → NP_652334.2  uncharacterized protein Dmel_CG18675 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_652334.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q8T478, Q9VZH1
    Related
    FBpp0073074
    Conserved Domains (1) summary
    pfam11069
    Location:189 → 285
    DUF2870; Protein of unknown function (DUF2870)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VZH1.2 Q9VZH1

Gene LinkOut

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Chemical Information
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