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Apol9a apolipoprotein L9a [ Rattus norvegicus (Norway rat) ]

Gene ID: 503164, updated on 4-Jan-2025

Summary

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Official Symbol
Apol9aprovided by RGD
Official Full Name
apolipoprotein L9aprovided by RGD
Primary source
RGD:1562332
See related
EnsemblRapid:ENSRNOG00000023410 AllianceGenome:RGD:1562332
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable lipid binding activity. Predicted to be involved in lipid transport and lipoprotein metabolic process. Predicted to be located in intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in schizophrenia. Orthologous to human APOL1 (apolipoprotein L1) and APOL2 (apolipoprotein L2). [provided by Alliance of Genome Resources, Jan 2025]
Expression
Biased expression in Heart (RPKM 223.4), Liver (RPKM 106.0) and 7 other tissues See more
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Genomic context

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See Apol9a in Genome Data Viewer
Location:
7q34
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 7 NC_086025.1 (111021452..111030380, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 7 NC_051342.1 (109140871..109149799, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (118927013..118933778, complement)

Chromosome 7 - NC_086025.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120093818 Neighboring gene Apol9a-Apol7a readthrough Neighboring gene apolipoprotein L7b, pseudogene 1 Neighboring gene apolipoprotein L3-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Readthrough Apol9a-Apol7a

Readthrough gene: Apol9a-Apol7a, Included gene: Apol7a

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables lipid binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in lipid transport IEA
Inferred from Electronic Annotation
more info
  
involved_in lipoprotein metabolic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
  
located_in intracellular membrane-bounded organelle ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
apolipoprotein L 9a

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001025066.2 → NP_001020237.1  apolipoprotein L 9a isoform 1

    See identical proteins and their annotated locations for NP_001020237.1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000007
    UniProtKB/TrEMBL
    Q5XIB6
    Related
    ENSRNOP00000036679.3, ENSRNOT00000031951.6
    Conserved Domains (1) summary
    pfam05461
    Location:1 → 313
    ApoL; Apolipoprotein L

  2. NM_001429364.1 → NP_001416293.1  apolipoprotein L 9a isoform 1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000007
    UniProtKB/TrEMBL
    Q5XIB6

  3. NM_001429365.1 → NP_001416294.1  apolipoprotein L 9a isoform 1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000007
    UniProtKB/TrEMBL
    Q5XIB6

  4. NM_001429366.1 → NP_001416295.1  apolipoprotein L 9a isoform 1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000007
    UniProtKB/TrEMBL
    Q5XIB6

  5. NM_001429367.1 → NP_001416296.1  apolipoprotein L 9a isoform 2

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000007

  6. NM_001429368.1 → NP_001416297.1  apolipoprotein L 9a isoform 2

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000007

  7. NM_001429369.1 → NP_001416298.1  apolipoprotein L 9a isoform 3

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000007

  8. NM_001429370.1 → NP_001416299.1  apolipoprotein L 9a isoform 4

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000007

  9. NM_001429377.1 → NP_001416306.1  apolipoprotein L 9a isoform 1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000007
    UniProtKB/TrEMBL
    Q5XIB6

  10. NM_001429378.1 → NP_001416307.1  apolipoprotein L 9a isoform 1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000007
    UniProtKB/TrEMBL
    Q5XIB6

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086025.1 Reference GRCr8

    Range
    111021452..111030380 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039079781.1 → XP_038935709.1  apolipoprotein L 9a isoform X1

    Conserved Domains (1) summary
    pfam05461
    Location:1 → 313
    ApoL; Apolipoprotein L

  2. XM_008765642.4 → XP_008763864.1  apolipoprotein L 9a isoform X2

    Conserved Domains (1) summary
    pfam05461
    Location:38 → 323
    ApoL; Apolipoprotein L

  3. XM_063264153.1 → XP_063120223.1  apolipoprotein L 9a isoform X1

Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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