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PRSS22 serine protease 22 [ Bos taurus (domestic cattle) ]

Gene ID: 510394, updated on 29-Jan-2025

Summary

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Official Symbol
PRSS22provided by VGNC
Official Full Name
serine protease 22provided by VGNC
Primary source
VGNC:VGNC:33415
See related
BGD:BT27827; Ensembl:ENSBTAG00000020582
Gene type
protein coding
RefSeq status
MODEL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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Genomic context

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See PRSS22 in Genome Data Viewer
Location:
chromosome: 25
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 25 NC_037352.1 (2178184..2182806)

Chromosome 25 - NC_037352.1Genomic Context describing neighboring genes Neighboring gene potassium channel tetramerization domain containing 5 Neighboring gene serine protease 27 Neighboring gene collagen alpha-1(III) chain Neighboring gene zymogen granule protein 16 homolog B Neighboring gene zymogen granule protein 16B

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037352.1 Chromosome 25 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Dominette sequence data
  • BioProject: PRJNA294306
  • Analysis date: Tue Dec 17 08:57:05 2024

Bibliography

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Related articles in PubMed

  1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables serine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
brain-specific serine protease 4
Names
protease, serine 22

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037352.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    2178184..2182806
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_002697927.6 → XP_002697973.3  brain-specific serine protease 4

    UniProtKB/TrEMBL
    A0A5F2P3F1, A0A8J8YA78, E1BNJ9, M5FI38
    Related
    ENSBTAP00070035994.1, ENSBTAT00070060594.1
    Conserved Domains (1) summary
    cd00190
    Location:21 → 259
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
Nucleotide Protein Strain
Heading Accession and Version

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