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TCOF1 treacle ribosome biogenesis factor 1 [ Bos taurus (domestic cattle) ]

Gene ID: 513591, updated on 30-Jan-2025

Summary

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Official Symbol
TCOF1provided by VGNC
Official Full Name
treacle ribosome biogenesis factor 1provided by VGNC
Primary source
VGNC:VGNC:35700
See related
BGD:BT23557; EnsemblRapid:ENSBTAG00070004751
Gene type
protein coding
RefSeq status
MODEL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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Genomic context

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See TCOF1 in Genome Data Viewer
Location:
chromosome: 7
Exon count:
27
Annotation release Status Assembly Chr Location
RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 7 NC_037334.1 (61708244..61746781)

Chromosome 7 - NC_037334.1Genomic Context describing neighboring genes Neighboring gene calcium/calmodulin dependent protein kinase II alpha Neighboring gene arylsulfatase family member I Neighboring gene uncharacterized LOC107132649 Neighboring gene CD74 molecule Neighboring gene ribosomal protein S14

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037334.1 Chromosome 7 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Dominette sequence data
  • BioProject: PRJNA294306
  • Analysis date: Tue Dec 17 08:57:05 2024

Bibliography

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Related articles in PubMed

  1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables RNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables scaffold protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in nucleolar large rRNA transcription by RNA polymerase I IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleolus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
treacle protein

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037334.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    61708244..61746781
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_002689293.7 → XP_002689339.2  treacle protein isoform X1

    See identical proteins and their annotated locations for XP_002689339.2

    UniProtKB/TrEMBL
    A6QP77, E1BHU1
    Related
    ENSBTAP00070006177.1, ENSBTAT00070010852.1
    Conserved Domains (2) summary
    smart00667
    Location:6 → 37
    LisH; Lissencephaly type-1-like homology motif
    pfam03546
    Location:319 → 840
    Treacle; Treacher Collins syndrome protein Treacle

  2. XM_010807517.4 → XP_010805819.1  treacle protein isoform X1

    See identical proteins and their annotated locations for XP_010805819.1

    UniProtKB/TrEMBL
    A6QP77, E1BHU1
    Conserved Domains (2) summary
    smart00667
    Location:6 → 37
    LisH; Lissencephaly type-1-like homology motif
    pfam03546
    Location:319 → 840
    Treacle; Treacher Collins syndrome protein Treacle

  3. XM_005209634.5 → XP_005209691.1  treacle protein isoform X3

    See identical proteins and their annotated locations for XP_005209691.1

    UniProtKB/TrEMBL
    A0A3Q1LFY9, A6QP77
    Related
    ENSBTAP00070006172.1, ENSBTAT00070010847.1
    Conserved Domains (2) summary
    smart00667
    Location:6 → 37
    LisH; Lissencephaly type-1-like homology motif
    pfam03546
    Location:319 → 840
    Treacle; Treacher Collins syndrome protein Treacle

  4. XM_059888793.1 → XP_059744776.1  treacle protein isoform X2

    UniProtKB/TrEMBL
    A0A3Q1LX56, A6QP77
    Related
    ENSBTAP00070006180.1, ENSBTAT00070010855.1

  5. XM_059888794.1 → XP_059744777.1  treacle protein isoform X4

  6. XM_024995260.2 → XP_024851028.1  treacle protein isoform X5

    Conserved Domains (2) summary
    smart00667
    Location:6 → 37
    LisH; Lissencephaly type-1-like homology motif
    pfam03546
    Location:319 → 840
    Treacle; Treacher Collins syndrome protein Treacle

RNA

  1. XR_807937.4 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version

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