WBP2NL WBP2 N-terminal like [Bos taurus (domestic cattle)] - Gene

Summary

Official Symbol: WBP2NLprovided by VGNC
Official Full Name: WBP2 N-terminal likeprovided by VGNC
Primary source: VGNC:VGNC:36873
See related: BGD:BT16691; Ensembl:ENSBTAG00000013174
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Bos taurus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 5

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
RS_2024_12	current	ARS-UCD2.0 (GCF_002263795.3)	5	NC_037332.1 (112982150..113011839)

Chromosome 5 - NC_037332.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_037332.1 Chromosome 5 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Dominette sequence data
BioProject: PRJNA294306
Analysis date: Tue Dec 17 08:57:05 2024

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

PAWP correlates with semen/fertility parameters used in the cattle artificial insemination industry, making PAWP a potential biomarker of bull fertility.
Title: Protein expression pattern of PAWP in bull spermatozoa is associated with sperm quality and fertility following artificial insemination.
PAWP is a sperm-specific WW domain-binding protein that promotes meiotic resumption and pronuclear development during fertilization
Title: PAWP, a sperm-specific WW domain-binding protein, promotes meiotic resumption and pronuclear development during fertilization.

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables chromatin DNA binding	IEA Inferred from Electronic Annotation more info	PubMed
enables transcription coactivator activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in positive regulation of DNA-templated transcription	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in nucleus	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: postacrosomal sheath WW domain-binding protein

Names: PAWP; WW domain-binding protein 2-like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001082441.2 → NP_001075910.1 postacrosomal sheath WW domain-binding protein

See identical proteins and their annotated locations for NP_001075910.1

Status: VALIDATED

Source sequence(s)

NKLS02000005

UniProtKB/Swiss-Prot

A3KFF6

Related

ENSBTAP00000017533.3, ENSBTAT00000017533.4

Conserved Domains (2) summary

cd13214
Location:43 → 134

PH-GRAM_WBP2; WW binding protein 2 (WB2) Pleckstrin Homology-Glucosyltransferases, Rab-like GTPase activators and Myotubularins (PH-GRAM) domain

pfam10349
Location:103 → 216

WWbp; WW-domain ligand protein