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Vhl - von Hippel-Lindau

Involved in several processes, including microtubule cytoskeleton organization; protein export from nucleus; and respiratory system development. Part of VCB complex. Is expressed in embryonic/larval tracheal dorsal trunk; embryonic/larval tracheal transverse connective; embryonic/larval visceral tracheal branch; and organism. Used to study von Hippel-Lindau disease. Human ortholog(s) of this gene implicated in several diseases, including pancreatic cancer (multiple); pheochromocytoma; polycythemia (multiple); renal cell carcinoma; and von Hippel-Lindau disease. Orthologous to several human genes including VHL (von Hippel-Lindau tumor suppressor). [provided by Alliance of Genome Resources, Dec 2024]

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Species Gene Architecture aa