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RecQ4 - RecQ4 helicase

Enables 3'-5' DNA helicase activity and single-stranded DNA binding activity. Involved in several processes, including DNA geometric change; DNA metabolic process; and positive regulation of G2/M transition of mitotic cell cycle. Located in chromatin; cytoplasm; and nucleus. Is expressed in several structures, including embryonic/larval optic lobe; embryonic/larval salivary gland; germinal proliferation center; germline cell; and imaginal disc. Human ortholog(s) of this gene implicated in Baller-Gerold syndrome; Rothmund-Thomson syndrome; and rapadilino syndrome. Orthologous to human RECQL4 (RecQ like helicase 4). [provided by Alliance of Genome Resources, Dec 2024]

Genes similar to RecQ4

NCBI Orthologs

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Species Gene Architecture aa