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lectin-33A lectin-33A [ Drosophila melanogaster (fruit fly) ]

Gene ID: 53516, updated on 9-Dec-2024

Summary

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Official Symbol
lectin-33Aprovided by FlyBase
Official Full Name
lectin-33Aprovided by FlyBase
Primary source
FLYBASE:FBgn0040096
Locus tag
Dmel_CG16834
See related
AllianceGenome:FB:FBgn0040096
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
AC 007083A; AC007083a; CG16834; Dmel\CG16834; lecti-33A; lectin-33a
Summary
Predicted to enable galactose binding activity. Human ortholog(s) of this gene implicated in extrapulmonary tuberculosis; pulmonary tuberculosis; and severe acute respiratory syndrome. Orthologous to several human genes including CLEC4A (C-type lectin domain family 4 member A); CLEC4C (C-type lectin domain family 4 member C); and CLEC4M (C-type lectin domain family 4 member M). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

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See lectin-33A in Genome Data Viewer
Location:
32C1-32C1; 2-44 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (11002072..11002738)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (11002072..11002738)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Tubulin tyrosine ligase-like 4A Neighboring gene aubergine Neighboring gene Ribosomal protein L9 Neighboring gene Nucleoporin 154kD Neighboring gene Arginine methyltransferase 8

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Whole-genome expression plasticity across tropical and temperate Drosophila melanogaster populations from Eastern Australia. Levine MT, et al. Mol Biol Evol, 2011 Jan. PMID 20671040, Free PMC Article
  2. A rapid genome-wide response to Drosophila melanogaster social interactions. Carney GE. BMC Genomics, 2007 Aug 22. PMID 17714588, Free PMC Article
  3. Insect glycobiology: a lectin multigene family in Drosophila melanogaster. Theopold U, et al. Biochem Biophys Res Commun, 1999 Aug 11. PMID 10441526
  4. Comparative genomic analysis of C-type lectin-domain genes in seven holometabolous insect species. Lu Y, et al. Insect Biochem Mol Biol, 2020 Nov. PMID 32841718
  5. Participation of a galactose-specific C-type lectin in Drosophila immunity. Tanji T, et al. Biochem J, 2006 May 15. PMID 16475980, Free PMC Article

See all (28) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables carbohydrate binding ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
enables galactose binding ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 

General protein information

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Preferred Names
lectin-33A
Names
CG16834-PB
lectin-33A-PB

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    11002072..11002738
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001103675.2 → NP_001097145.1  lectin-33A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001097145.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VKL8
    Conserved Domains (1) summary
    smart00034
    Location:24 → 157
    CLECT; C-type lectin (CTL) or carbohydrate-recognition domain (CRD)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VKL8 Q9VKL8

Gene LinkOut

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