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lectin-24Db lectin-24Db [ Drosophila melanogaster (fruit fly) ]

Gene ID: 53550, updated on 9-Dec-2024

Summary

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Official Symbol
lectin-24Dbprovided by FlyBase
Official Full Name
lectin-24Dbprovided by FlyBase
Primary source
FLYBASE:FBgn0040102
Locus tag
Dmel_CG2958
See related
AllianceGenome:FB:FBgn0040102
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
AC 004371A; AC004371a; CG2958; Dmel\CG2958; Lectin 24Db
Summary
Enables D-mannose binding activity; fucose binding activity; and glycosylated region protein binding activity. Predicted to be involved in immune response. Predicted to be located in extracellular region. Predicted to be active in external side of plasma membrane. Is expressed in adult head. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See lectin-24Db in Genome Data Viewer
Location:
24D8-24D8; 2-11 cM
Exon count:
1
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (4188123..4189284)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (4188123..4189284)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR45791 Neighboring gene long non-coding RNA:CR44057 Neighboring gene Tubulin-binding cofactor C Neighboring gene Nicotinate phosphoribosyltransferase Neighboring gene fat

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. An endogenous Drosophila receptor for glycans bearing alpha 1,3-linked core fucose residues. Bouyain S, et al. J Biol Chem, 2002 Jun 21. PMID 11960993
  2. A rapid genome-wide response to Drosophila melanogaster social interactions. Carney GE. BMC Genomics, 2007 Aug 22. PMID 17714588, Free PMC Article
  3. Glycosylation of proteins in plants and invertebrates. Wilson IB. Curr Opin Struct Biol, 2002 Oct. PMID 12464307
  4. The genomic basis of copper tolerance in Drosophila is shaped by a complex interplay of regulatory and environmental factors. Green L, et al. BMC Biol, 2022 Dec 8. PMID 36482348, Free PMC Article
  5. Molecular evolution and population genetics of duplicated accessory gland protein genes in Drosophila. Holloway AK, et al. Mol Biol Evol, 2004 Sep. PMID 15215320

See all (35) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. a potential endogenous receptor for neural-specific carbohydrate epitopes
    Title: An endogenous Drosophila receptor for glycans bearing alpha 1,3-linked core fucose residues.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables D-mannose binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables carbohydrate binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables fucose binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables glycosylated region protein binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables pattern recognition receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in immune response IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in external side of plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in extracellular region ISM
Inferred from Sequence Model
more info
 PubMed 

General protein information

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Preferred Names
lectin-24Db
Names
CG2958-PA
Lectin24DB
lectin
lectin-24Db-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    4188123..4189284
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_144384.3 → NP_652641.1  lectin-24Db [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_652641.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VQX3
    Related
    FBpp0077158
    Conserved Domains (3) summary
    cd00037
    Location:247 → 354
    CLECT; C-type lectin (CTL)/C-type lectin-like (CTLD) domain
    pfam16806
    Location:44 → 156
    ExsD; Antiactivator protein ExsD
    cl17182
    Location:170 → 229
    NAT_SF; N-Acyltransferase superfamily: Various enyzmes that characteristicly catalyze the transfer of an acyl group to a substrate
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VQX3 Q9VQX3

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