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MARCHF6 membrane associated ring-CH-type finger 6 [ Bos taurus (domestic cattle) ]

Gene ID: 540371, updated on 29-Jan-2025

Summary

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Official Symbol
MARCHF6provided by VGNC
Official Full Name
membrane associated ring-CH-type finger 6provided by VGNC
Primary source
VGNC:VGNC:31241
See related
BGD:BT17205; Ensembl:ENSBTAG00000003536
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Also known as
MARCH6
Orthologs
human mouse all
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Genomic context

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See MARCHF6 in Genome Data Viewer
Location:
chromosome: 20
Exon count:
27
Annotation release Status Assembly Chr Location
RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 20 NC_037347.1 (62819405..62899708, complement)

Chromosome 20 - NC_037347.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC112443012 Neighboring gene uncharacterized LOC112443013 Neighboring gene rhophilin associated tail protein 1 like Neighboring gene transfer RNA cysteine (anticodon ACA) Neighboring gene microRNA mir-6530 Neighboring gene carboxymethylenebutenolidase homolog Neighboring gene chaperonin containing TCP1 subunit 5

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037347.1 Chromosome 20 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Dominette sequence data
  • BioProject: PRJNA294306
  • Analysis date: Tue Dec 17 08:57:05 2024

Bibliography

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Related articles in PubMed

  1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
E3 ubiquitin-protein ligase MARCHF6
Names
membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase
NP_001192741.1
XP_024837125.1
XP_024837126.1
XP_059734753.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001205812.3 → NP_001192741.1  E3 ubiquitin-protein ligase MARCHF6

    See identical proteins and their annotated locations for NP_001192741.1

    Status: VALIDATED

    Source sequence(s)
    EV626671, EV632242, EV706277, NKLS02000020
    UniProtKB/TrEMBL
    F1MHF0
    Related
    ENSBTAP00070025365.1, ENSBTAT00070042478.1
    Conserved Domains (2) summary
    smart00744
    Location:8 → 56
    RINGv; The RING-variant domain is a C4HC3 zinc-finger like motif found in a number of cellular and viral proteins
    PHA03419
    Location:125 → 214
    PHA03419; E4 protein; Provisional

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037347.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    62819405..62899708 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_059878770.1 → XP_059734753.1  E3 ubiquitin-protein ligase MARCHF6 isoform X2

    UniProtKB/TrEMBL
    A0AAA9S2H9, F1MHF0
    Related
    ENSBTAP00070025380.1, ENSBTAT00070042503.1

  2. XM_024981358.2 → XP_024837126.1  E3 ubiquitin-protein ligase MARCHF6 isoform X1

    UniProtKB/TrEMBL
    A0AAA9T0G2
    Related
    ENSBTAP00070025351.1, ENSBTAT00070042454.1
    Conserved Domains (1) summary
    COG5183
    Location:314 → 840
    SSM4; E3 ubiquitin-protein ligase DOA10 [Posttranslational modification, protein turnover, chaperones]

  3. XM_024981357.2 → XP_024837125.1  E3 ubiquitin-protein ligase MARCHF6 isoform X1

    UniProtKB/TrEMBL
    A0AAA9T0G2
    Conserved Domains (1) summary
    COG5183
    Location:314 → 840
    SSM4; E3 ubiquitin-protein ligase DOA10 [Posttranslational modification, protein turnover, chaperones]
Nucleotide Protein Strain
Heading Accession and Version

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