cirbpa cold inducible RNA binding protein a [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: cirbpaprovided by ZNC
Official Full Name: cold inducible RNA binding protein aprovided by ZNC
Primary source: ZFIN:ZDB-GENE-050417-329
See related: Ensembl:ENSDARG00000103672 AllianceGenome:ZFIN:ZDB-GENE-050417-329
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: wu:fb12a12; wu:fb16h02; wu:fb55a06; wu:fc67h01; wu:fj10g10; zgc:109887; zgc:112425
Summary: Predicted to enable RNA binding activity. Predicted to be involved in positive regulation of mRNA splicing, via spliceosome. Predicted to be part of spliceosomal complex. Is expressed in digestive system; nervous system; and pectoral fin. Orthologous to several human genes including CIRBP (cold inducible RNA binding protein). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs: all
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Genomic context

Location:: chromosome: 2

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	2	NC_007113.7 (58841181..58848887)
105	previous assembly	GRCz10 (GCF_000002035.5)	2	NC_007113.6 (58654657..58662363)

Chromosome 2 - NC_007113.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

A proteomics approach identifies novel resident zebrafish Balbiani body proteins Cirbpa and Cirbpb.
Title: A proteomics approach identifies novel resident zebrafish Balbiani body proteins Cirbpa and Cirbpb.

Submit: New GeneRIF Correction

General gene information

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Markers

fj10g10.x1 (e-PCR)
- UniSTS:188419

fc67h01.x1 (e-PCR)
- UniSTS:188218

fb12a12.x1 (e-PCR)
- UniSTS:202856

AI477779 (e-PCR)
- UniSTS:206441

fb44g09.x1 (e-PCR)
- UniSTS:190593

fb16h02.x1 (e-PCR)
- UniSTS:202975

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables RNA binding	IBA Inferred from Biological aspect of Ancestor more info
enables RNA binding	IEA Inferred from Electronic Annotation more info
enables nucleic acid binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in positive regulation of mRNA splicing, via spliceosome	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
part_of spliceosomal complex	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: cold inducible RNA binding protein a

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001017797.1 → NP_001017797.1 cold inducible RNA binding protein a

See identical proteins and their annotated locations for NP_001017797.1

Status: PROVISIONAL

Source sequence(s)

BC093299

UniProtKB/TrEMBL

A0A0R4II63, B2GRU2, Q566W6

Conserved Domains (2) summary

COG0724
Location:2 → 81

RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]

cl17169
Location:5 → 83

RRM_SF; RNA recognition motif (RRM) superfamily