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tmeff1b transmembrane protein with EGF-like and two follistatin-like domains 1b [ Danio rerio (zebrafish) ]

Gene ID: 553511, updated on 4-Jan-2025

Summary

Official Symbol
tmeff1bprovided by ZNC
Official Full Name
transmembrane protein with EGF-like and two follistatin-like domains 1bprovided by ZNC
Primary source
ZFIN:ZDB-GENE-050706-143
See related
Ensembl:ENSDARG00000056740 AllianceGenome:ZFIN:ZDB-GENE-050706-143
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
tmeff1; fb53c10; wu:fb53c10; zgc:110069
Summary
Predicted to be involved in cell differentiation. Predicted to be located in membrane. Predicted to be active in extracellular region. Orthologous to several human genes including TMEFF1 (transmembrane protein with EGF like and two follistatin like domains 1). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
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Genomic context

See tmeff1b in Genome Data Viewer
Location:
chromosome: 24
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 24 NC_007135.7 (33708804..33756003, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 24 NC_007135.6 (33822629..33869828, complement)

Chromosome 24 - NC_007135.7Genomic Context describing neighboring genes Neighboring gene dynein, axonemal, heavy chain 5 like Neighboring gene golgin subfamily A member 6-like protein 24 Neighboring gene caveolae associated protein 4b Neighboring gene cyclin dependent kinase 5 Neighboring gene ATP-binding cassette, sub-family B (MDR/TAP), member 8

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Markers

Clone Names

  • MGC110069

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in cell differentiation IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in extracellular region IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
tomoregulin-1b
Names
transmembrane protein with EGF-like and two follistatin-like domains 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001025301.1NP_001020472.1  tomoregulin-1b

    See identical proteins and their annotated locations for NP_001020472.1

    Status: PROVISIONAL

    Source sequence(s)
    BC098543
    UniProtKB/TrEMBL
    Q4KMI9
    Related
    ENSDARP00000073739.5, ENSDART00000079283.6
    Conserved Domains (2) summary
    PHA02887
    Location:263300
    PHA02887; EGF-like protein; Provisional
    smart00280
    Location:89134
    KAZAL; Kazal type serine protease inhibitors

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007135.7 Reference GRCz11 Primary Assembly

    Range
    33708804..33756003 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)