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rab12 RAB12, member RAS oncogene family [ Danio rerio (zebrafish) ]

Gene ID: 553657, updated on 4-Jan-2025

Summary

Official Symbol
rab12provided by ZNC
Official Full Name
RAB12, member RAS oncogene familyprovided by ZNC
Primary source
ZFIN:ZDB-GENE-050522-555
See related
Ensembl:ENSDARG00000089428 AllianceGenome:ZFIN:ZDB-GENE-050522-555
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:111945
Summary
Predicted to enable GTPase activity. Predicted to be involved in endocytic recycling and exocytosis. Predicted to act upstream of or within Rab protein signal transduction. Predicted to be active in cytoplasmic vesicle and plasma membrane. Is expressed in hindbrain; neural crest; and pharyngeal arch. Orthologous to human RAB12 (RAB12, member RAS oncogene family). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
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Genomic context

See rab12 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 2 NC_007113.7 (54387710..54419031)
105 previous assembly GRCz10 (GCF_000002035.5) 2 NC_007113.6 (54663063..54694384)

Chromosome 2 - NC_007113.7Genomic Context describing neighboring genes Neighboring gene cathepsin Z Neighboring gene piezo type mechanosensitive ion channel component 2 Neighboring gene uncharacterized LOC101882917 Neighboring gene N-ethylmaleimide-sensitive factor attachment protein, gamma b Neighboring gene microtubule crosslinking factor 1 Neighboring gene acyl-CoA synthetase short chain family member 2 like

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Clone Names

  • MGC111945

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables GTP binding IEA
Inferred from Electronic Annotation
more info
 
enables GTPase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables GTPase activity IEA
Inferred from Electronic Annotation
more info
 
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within Rab protein signal transduction IEA
Inferred from Electronic Annotation
more info
 
involved_in endocytic recycling IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in exocytosis IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in endosome IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in synaptic vesicle IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in trans-Golgi network transport vesicle IBA
Inferred from Biological aspect of Ancestor
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001020630.1NP_001018466.1  ras-related protein Rab-12

    See identical proteins and their annotated locations for NP_001018466.1

    Status: PROVISIONAL

    Source sequence(s)
    BC095608
    UniProtKB/TrEMBL
    B2GS97, F6P1S2, Q502Q0
    Related
    ENSDARP00000110018.1, ENSDART00000127124.2
    Conserved Domains (2) summary
    smart00175
    Location:36200
    RAB; Rab subfamily of small GTPases
    cd04120
    Location:36235
    Rab12; Rab GTPase family 12 (Rab12)

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007113.7 Reference GRCz11 Primary Assembly

    Range
    54387710..54419031
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)