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cfhl4 complement factor H like 4 [ Danio rerio (zebrafish) ]

Gene ID: 559122, updated on 2-Nov-2024

Summary

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Official Symbol
cfhl4provided by ZNC
Official Full Name
complement factor H like 4provided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-251
See related
Ensembl:ENSDARG00000102456 AllianceGenome:ZFIN:ZDB-GENE-030131-251
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
cfhl2; cfhr2; im:7037131; wu:fb18c08; si:ch211-207o17.1
Summary
Is expressed in several structures, including digestive system; eye; fin; gill; and heart. Orthologous to several human genes including F13B (coagulation factor XIII B chain). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
all
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Genomic context

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See cfhl4 in Genome Data Viewer
Location:
chromosome: 22
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 22 NC_007133.7 (23613706..23625360, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 22 NC_007133.6 (23587102..23598796, complement)

Chromosome 22 - NC_007133.7Genomic Context describing neighboring genes Neighboring gene complement factor H-related protein 3-like Neighboring gene complement factor H like 5 Neighboring gene complement factor H Neighboring gene complement factor H like 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Zebrafish complement factor H and its related genes: identification, evolution, and expression. Sun G, et al. Funct Integr Genomics, 2010 Nov. PMID 20668901
  2. Regulator of complement activation (RCA) group 2 gene cluster in zebrafish: identification, expression, and evolution. Wu J, et al. Funct Integr Genomics, 2012 Jun. PMID 22252228
  3. Identification and expression of liver-specific genes after LPS challenge in amphioxus: the hepatic cecum as liver-like organ and "pre-hepatic" acute phase response. Wang Y, et al. Funct Integr Genomics, 2011 Mar. PMID 21052758
  4. The zebrafish gene map defines ancestral vertebrate chromosomes. Woods IG, et al. Genome Res, 2005 Sep. PMID 16109975, Free PMC Article
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

General protein information

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Preferred Names
complement factor H like 4
Names
complement factor H-related 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001199366.1 → NP_001186295.1  complement factor H like 4 precursor

    See identical proteins and their annotated locations for NP_001186295.1

    Status: PROVISIONAL

    Source sequence(s)
    HM149236
    UniProtKB/TrEMBL
    E2FHP8
    Related
    ENSDARP00000138093.1, ENSDART00000163423.2
    Conserved Domains (2) summary
    cd00033
    Location:95 → 152
    CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system
    PHA02927
    Location:309 → 471
    PHA02927; secreted complement-binding protein; Provisional

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007133.7 Reference GRCz11 Primary Assembly

    Range
    23613706..23625360 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018395107.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    170428..188260 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

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