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atp5mea ATP synthase membrane subunit ea [ Danio rerio (zebrafish) ]

Gene ID: 559659, updated on 4-Jan-2025

Summary

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Official Symbol
atp5meaprovided by ZNC
Official Full Name
ATP synthase membrane subunit eaprovided by ZNC
Primary source
ZFIN:ZDB-GENE-070928-12
See related
Ensembl:ENSDARG00000078113 AllianceGenome:ZFIN:ZDB-GENE-070928-12
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
atp5ia; zgc:171560
Summary
Predicted to enable proton transmembrane transporter activity. Predicted to act upstream of or within proton motive force-driven ATP synthesis and proton transmembrane transport. Predicted to be located in mitochondrial inner membrane. Predicted to be part of proton-transporting ATP synthase complex. Orthologous to human ATP5ME (ATP synthase membrane subunit e). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
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Genomic context

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See atp5mea in Genome Data Viewer
Location:
chromosome: 21
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 21 NC_007132.7 (20377890..20381467, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 21 NC_007132.6 (20341254..20344831, complement)

Chromosome 21 - NC_007132.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC101886495 Neighboring gene retinol binding protein 4, like Neighboring gene phosphodiesterase 6B, cGMP-specific, rod, beta Neighboring gene si:dkey-30k6.5 Neighboring gene heat shock protein, alpha-crystallin-related, b9-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Transcriptomic analysis reveals mitochondrial dysfunction in the pathogenesis of Nager syndrome in sf3b4-depleted zebrafish. Ulhaq ZS, et al. Biochim Biophys Acta Mol Basis Dis, 2024 Apr. PMID 38508476
  2. The developmental effects of pentachlorophenol on zebrafish embryos during segmentation: A systematic view. Xu T, et al. Sci Rep, 2016 May 16. PMID 27181905, Free PMC Article
  3. Aclonifen causes developmental abnormalities in zebrafish embryos through mitochondrial dysfunction and oxidative stress. Lee JY, et al. Sci Total Environ, 2021 Jun 1. PMID 33548715
  4. Spatio-temporal regulation of Wnt and retinoic acid signaling by tbx16/spadetail during zebrafish mesoderm differentiation. Mueller RL, et al. BMC Genomics, 2010 Sep 9. PMID 20828405, Free PMC Article
  5. Copper Regulates the Susceptibility of Zebrafish Larvae to Inflammatory Stimuli by Controlling Neutrophil/Macrophage Survival. Chen M, et al. Front Immunol, 2019. PMID 31787979, Free PMC Article

See all (10) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Clone Names

  • MGC171560

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables proton transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within ATP biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within monoatomic ion transport IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within proton motive force-driven ATP synthesis IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within proton transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in mitochondrial inner membrane IEA
Inferred from Electronic Annotation
more info
  
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
  
part_of proton-transporting ATP synthase complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of proton-transporting ATP synthase complex, coupling factor F(o) IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
ATP synthase membrane subunit ea
Names
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit e, duplicate a
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit Ea

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001172637.1 → NP_001166108.1  ATP synthase membrane subunit ea

    Status: VALIDATED

    Source sequence(s)
    AL844141, BC152574
    UniProtKB/TrEMBL
    A0A8M1NW06, A7YY99
    Related
    ENSDARP00000098791.2, ENSDART00000115236.3
    Conserved Domains (1) summary
    pfam05680
    Location:2 → 35
    ATP-synt_E; ATP synthase E chain

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007132.7 Reference GRCz11 Primary Assembly

    Range
    20377890..20381467 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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