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ywhag2 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 2 [ Danio rerio (zebrafish) ]

Gene ID: 560560, updated on 2-Nov-2024

Summary

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Official Symbol
ywhag2provided by ZNC
Official Full Name
3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 2provided by ZNC
Primary source
ZFIN:ZDB-GENE-061023-2
See related
Ensembl:ENSDARG00000071658 AllianceGenome:ZFIN:ZDB-GENE-061023-2
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
ywhagl
Summary
Predicted to enable protein kinase C binding activity. Predicted to be involved in protein localization and signal transduction. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 56. Orthologous to human YWHAG (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
all
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Genomic context

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See ywhag2 in Genome Data Viewer
Location:
chromosome: 15
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 15 NC_007126.7 (15349165..15357141, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 15 NC_007126.6 (15412880..15421149, complement)

Chromosome 15 - NC_007126.7Genomic Context describing neighboring genes Neighboring gene C2 domain containing 3 centriole elongation regulator Neighboring gene calcium/calmodulin-dependent protein kinase kinase 1, alpha b Neighboring gene si:ch211-105f12.2 Neighboring gene microRNA 142b

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Expression analysis of the family of 14-3-3 proteins in zebrafish development. Besser J, et al. Gene Expr Patterns, 2007 Feb. PMID 17127101
  2. Comparative and evolutionary analysis of the 14-3-3 family genes in eleven fishes. Cao J, et al. Gene, 2018 Jul 1. PMID 29653226
  3. On the crucial cerebellar wound healing-related pathways and their cross-talks after traumatic brain injury in Danio rerio. Wu CC, et al. PLoS One, 2014. PMID 24926785, Free PMC Article
  4. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
  5. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables protein kinase C binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in protein localization IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
14-3-3 protein gamma-1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007126.7 Reference GRCz11 Primary Assembly

    Range
    15349165..15357141 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_683958.9 → XP_689050.2  14-3-3 protein gamma-1

    UniProtKB/TrEMBL
    A0A8M9PNI4, E7F354
    Related
    ENSDARP00000096898.3, ENSDART00000106120.5
    Conserved Domains (1) summary
    cd10024
    Location:2 → 247
    14-3-3_gamma; 14-3-3 gamma, an isoform of 14-3-3 protein

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018394939.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    195763..203739 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021472913.2 → XP_021328588.1  14-3-3 protein gamma-1

    UniProtKB/TrEMBL
    A0A8M9PNI4, E7F354
    Conserved Domains (1) summary
    cd10024
    Location:2 → 247
    14-3-3_gamma; 14-3-3 gamma, an isoform of 14-3-3 protein
Nucleotide Protein Strain
Heading Accession and Version

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