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Gltp glycolipid transfer protein [ Mus musculus (house mouse) ]

Gene ID: 56356, updated on 27-Nov-2024

Summary

Official Symbol
Gltpprovided by MGI
Official Full Name
glycolipid transfer proteinprovided by MGI
Primary source
MGI:MGI:1929253
See related
Ensembl:ENSMUSG00000011884 AllianceGenome:MGI:1929253
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
1110001F24Rik
Summary
Predicted to enable several functions, including ceramide 1-phosphate binding activity; ceramide 1-phosphate transfer activity; and identical protein binding activity. Predicted to be involved in ceramide transport and intermembrane lipid transfer. Predicted to be active in cytosol. Is expressed in several structures, including cerebral cortex ventricular layer; meninges; naris; and thymus primordium. Orthologous to human GLTP (glycolipid transfer protein). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Ubiquitous expression in stomach adult (RPKM 119.7), lung adult (RPKM 84.5) and 26 other tissues See more
Orthologs
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Genomic context

See Gltp in Genome Data Viewer
Location:
5 F; 5 55.99 cM
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (114807551..114828996, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (114669490..114690935, complement)

Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene family with sequence similarity 222, member A Neighboring gene STARR-positive B cell enhancer ABC_E8071 Neighboring gene CapStarr-seq enhancer MGSCv37_chr5:115047361-115047562 Neighboring gene predicted gene, 34844 Neighboring gene transient receptor potential cation channel, subfamily V, member 4 Neighboring gene STARR-positive B cell enhancer ABC_E2757 Neighboring gene STARR-positive B cell enhancer ABC_E9261 Neighboring gene STARR-seq mESC enhancer starr_14082 Neighboring gene predicted gene, 34931 Neighboring gene STARR-positive B cell enhancer ABC_E10341 Neighboring gene trichoplein, keratin filament binding Neighboring gene microRNA 7028

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 
  • Gene trapped (1) 
  • Targeted (1) 

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables ceramide 1-phosphate binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables ceramide 1-phosphate transfer activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables glycolipid binding ISO
Inferred from Sequence Orthology
more info
 
enables glycolipid binding ISS
Inferred from Sequence or Structural Similarity
more info
 
enables identical protein binding IEA
Inferred from Electronic Annotation
more info
 
enables identical protein binding ISO
Inferred from Sequence Orthology
more info
 
enables lipid binding ISO
Inferred from Sequence Orthology
more info
 
enables lipid binding ISS
Inferred from Sequence or Structural Similarity
more info
 
enables lipid transfer activity ISO
Inferred from Sequence Orthology
more info
 
enables lipid transfer activity ISS
Inferred from Sequence or Structural Similarity
more info
 
Process Evidence Code Pubs
involved_in ceramide transport IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in intermembrane lipid transfer IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in intermembrane lipid transfer ISO
Inferred from Sequence Orthology
more info
 
involved_in intermembrane lipid transfer ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in response to immobilization stress IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
glycolipid transfer protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_019821.2NP_062795.2  glycolipid transfer protein

    See identical proteins and their annotated locations for NP_062795.2

    Status: PROVISIONAL

    Source sequence(s)
    BC016584
    Consensus CDS
    CCDS19569.1
    UniProtKB/Swiss-Prot
    Q91YJ7, Q9CTK9, Q9JL62
    UniProtKB/TrEMBL
    Q3U011
    Related
    ENSMUSP00000012028.8, ENSMUST00000012028.14
    Conserved Domains (1) summary
    pfam08718
    Location:22166
    GLTP; Glycolipid transfer protein (GLTP)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000071.7 Reference GRCm39 C57BL/6J

    Range
    114807551..114828996 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)