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sema3e - sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E

Enables neuropilin binding activity. Acts upstream of or within neural crest cell migration and sprouting angiogenesis. Predicted to be active in extracellular space and plasma membrane. Is expressed in several structures, including cardiovascular system; endoderm; head; immature eye; and nervous system. Used to study CHARGE syndrome. Orthologous to human SEMA3E (semaphorin 3E). [provided by Alliance of Genome Resources, Dec 2024]

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Species Gene Architecture aa