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dad1 defender against cell death 1 [ Danio rerio (zebrafish) ]

Gene ID: 566527, updated on 4-Jan-2025

Summary

Official Symbol
dad1provided by ZNC
Official Full Name
defender against cell death 1provided by ZNC
Primary source
ZFIN:ZDB-GENE-060503-233
See related
Ensembl:ENSDARG00000102105 AllianceGenome:ZFIN:ZDB-GENE-060503-233
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
si:ch211-9d9.5
Summary
Predicted to be involved in protein N-linked glycosylation. Predicted to be located in endoplasmic reticulum and membrane. Predicted to be part of oligosaccharyltransferase complex. Orthologous to human DAD1 (defender against cell death 1). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
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Genomic context

See dad1 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 2 NC_007113.7 (51640849..51644034, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 2 NC_007113.6 (52048087..52051272, complement)

Chromosome 2 - NC_007113.7Genomic Context describing neighboring genes Neighboring gene polymeric immunoglobulin receptor Neighboring gene polymeric immunoglobulin receptor Neighboring gene abhydrolase domain containing 4, N-acyl phospholipase B Neighboring gene transglutaminase 1 like 1

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Markers

Gene Ontology Provided by ZFIN

Process Evidence Code Pubs
involved_in protein N-linked glycosylation IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
part_of oligosaccharyltransferase complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of oligosaccharyltransferase complex IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1
NP_001093909.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001100439.1NP_001093909.1  dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1

    See identical proteins and their annotated locations for NP_001093909.1

    Status: PROVISIONAL

    Source sequence(s)
    BC150399
    UniProtKB/TrEMBL
    A0A8M1NEA1, A7E2L0
    Related
    ENSDARP00000132059.1, ENSDART00000157899.2
    Conserved Domains (1) summary
    pfam02109
    Location:7113
    DAD; DAD family

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007113.7 Reference GRCz11 Primary Assembly

    Range
    51640849..51644034 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)