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lepA translation elongation factor 4 [ Cronobacter sakazakii ]

Gene ID: 56729579, updated on 6-Jun-2024

Summary

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Gene symbol
lepA
Gene description
translation elongation factor 4
Locus tag
CsakCS931_RS00795
Gene type
protein coding
Organism
Cronobacter sakazakii (strain: CS-931, nat-host: Homo sapiens)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Cronobacter
Old locus tag
CsakCS931_21005
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Genomic context

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NZ_CP027107.1Genomic Context describing neighboring genes Neighboring gene anti-sigma-E factor RseA Neighboring gene sigma-E factor regulatory protein RseB Neighboring gene SoxR-reducing system protein RseC Neighboring gene signal peptidase I Neighboring gene ribonuclease III Neighboring gene GTPase Era

Genomic regions, transcripts, and products

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Genomic Sequence:
NZ_CP027107.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Novel Multidrug-Resistant Cronobacter sakazakii Causing Meningitis in Neonate, China, 2015. Zeng H, et al. Emerg Infect Dis, 2018 Nov. PMID 30334728, Free PMC Article
  2. EF4 reveals the energy barrier for tRNA back-translocation in the peptidyl transferase center. Song G, et al. RNA Biol, 2016 Oct 2. PMID 27472653, Free PMC Article
  3. Structure of the GTP Form of Elongation Factor 4 (EF4) Bound to the Ribosome. Kumar V, et al. J Biol Chem, 2016 Jun 17. PMID 27137929, Free PMC Article
  4. The conserved protein EF4 (LepA) modulates the elongation cycle of protein synthesis. Liu H, et al. Proc Natl Acad Sci U S A, 2011 Sep 27. PMID 21930951, Free PMC Article
  5. Conserved GTPase LepA (Elongation Factor 4) functions in biogenesis of the 30S subunit of the 70S ribosome. Gibbs MR, et al. Proc Natl Acad Sci U S A, 2017 Jan 31. PMID 28096346, Free PMC Article

GeneRIFs: Gene References Into Functions

General protein information

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Preferred Names
translation elongation factor 4
WP_004387377.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NZ_CP027107.1 Reference assembly

    Range
    171919..173718
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. WP_004387377.1 MULTISPECIES: translation elongation factor 4 [Cronobacter]

    See identical proteins and their annotated locations for WP_004387377.1

    UniProtKB/Swiss-Prot
    A7MH13
    UniProtKB/TrEMBL
    A0A2S9U9N2, V5TVN9
Nucleotide Protein
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