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kifc3 kinesin family member C3 [ Danio rerio (zebrafish) ]

Gene ID: 568367, updated on 4-Jan-2025

Summary

Official Symbol
kifc3provided by ZNC
Official Full Name
kinesin family member C3provided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-3724
See related
AllianceGenome:ZFIN:ZDB-GENE-030131-3724
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
fc51b05; wu:fc51b05; si:ch211-160j6.2
Summary
Predicted to enable ATP binding activity; microtubule binding activity; and microtubule motor activity. Predicted to be involved in system development. Predicted to act upstream of or within microtubule-based movement. Predicted to be located in cytoplasm and microtubule. Orthologous to human KIFC3 (kinesin family member C3). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
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Genomic context

See kifc3 in Genome Data Viewer
Location:
chromosome: 18
Exon count:
28
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 18 NC_007129.7 (45526550..45592410)
105 previous assembly GRCz10 (GCF_000002035.5) 18 NC_007129.6 (45529560..45595456)

Chromosome 18 - NC_007129.7Genomic Context describing neighboring genes Neighboring gene LARGE xylosyl- and glucuronyltransferase 2 Neighboring gene uncharacterized LOC110438109 Neighboring gene cyclic nucleotide gated channel subunit beta 1a Neighboring gene uncharacterized LOC108180032 Neighboring gene WT1 transcription factor b Neighboring gene eukaryotic translation initiation factor 3, subunit M

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Markers

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables microtubule binding IEA
Inferred from Electronic Annotation
more info
 
enables microtubule motor activity IEA
Inferred from Electronic Annotation
more info
 
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within microtubule-based movement IEA
Inferred from Electronic Annotation
more info
 
involved_in system development IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
 
located_in microtubule IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
kinesin-like protein KIFC3
Names
novel kinesin motor domain containing protein

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007129.7 Reference GRCz11 Primary Assembly

    Range
    45526550..45592410
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_068214958.1XP_068071059.1  kinesin-like protein KIFC3 isoform X13

    UniProtKB/TrEMBL
    A0A8M9PFZ6
  2. XM_009293855.3XP_009292130.1  kinesin-like protein KIFC3 isoform X14

    See identical proteins and their annotated locations for XP_009292130.1

    UniProtKB/TrEMBL
    A0A8M3B361, A0A8M9PFZ6
    Conserved Domains (4) summary
    smart00129
    Location:566895
    KISc; Kinesin motor, catalytic domain. ATPase
    cd01366
    Location:564891
    KISc_C_terminal; Kinesin motor domain, KIFC2/KIFC3/ncd-like carboxy-terminal kinesins
    pfam15619
    Location:208386
    Lebercilin; Ciliary protein causing Leber congenital amaurosis disease
    cl01090
    Location:362407
    SlyX; SlyX
  3. XM_068214961.1XP_068071062.1  kinesin-like protein KIFC3 isoform X16

    UniProtKB/TrEMBL
    A0A8M9PFZ6
  4. XM_068214962.1XP_068071063.1  kinesin-like protein KIFC3 isoform X17

    UniProtKB/TrEMBL
    A0A8M9PFZ6
  5. XM_068214947.1XP_068071048.1  kinesin-like protein KIFC3 isoform X1

    UniProtKB/TrEMBL
    A0A8M3AV59
  6. XM_068214950.1XP_068071051.1  kinesin-like protein KIFC3 isoform X5

    UniProtKB/TrEMBL
    A0A8M3AS77
  7. XM_068214948.1XP_068071049.1  kinesin-like protein KIFC3 isoform X2

    UniProtKB/TrEMBL
    A0A8M3AV59
  8. XM_068214949.1XP_068071050.1  kinesin-like protein KIFC3 isoform X3

    UniProtKB/TrEMBL
    A0A8M2B5V3
  9. XM_068214951.1XP_068071052.1  kinesin-like protein KIFC3 isoform X6

    UniProtKB/TrEMBL
    A0A8M3AS77
  10. XM_068214952.1XP_068071053.1  kinesin-like protein KIFC3 isoform X7

    UniProtKB/TrEMBL
    A0A8M3AS77
  11. XM_009293849.4XP_009292124.1  kinesin-like protein KIFC3 isoform X4

    UniProtKB/TrEMBL
    A0A8M3AKN3, A0A8M3AV59
    Conserved Domains (5) summary
    smart00129
    Location:6791008
    KISc; Kinesin motor, catalytic domain. ATPase
    cd01366
    Location:6771004
    KISc_C_terminal; Kinesin motor domain, KIFC2/KIFC3/ncd-like carboxy-terminal kinesins
    pfam05667
    Location:93438
    DUF812; Protein of unknown function (DUF812)
    pfam15619
    Location:321499
    Lebercilin; Ciliary protein causing Leber congenital amaurosis disease
    cl01090
    Location:475520
    SlyX; SlyX
  12. XM_068214953.1XP_068071054.1  kinesin-like protein KIFC3 isoform X8

    UniProtKB/TrEMBL
    A0A8M3AS77
  13. XM_068214954.1XP_068071055.1  kinesin-like protein KIFC3 isoform X9

    UniProtKB/TrEMBL
    A0A8M3AS77
  14. XM_009293853.4XP_009292128.1  kinesin-like protein KIFC3 isoform X10

    UniProtKB/TrEMBL
    A0A8M3AJU8, A0A8M3AS77
    Conserved Domains (5) summary
    TIGR02559
    Location:388551
    HrpB7; type III secretion protein HrpB7
    smart00129
    Location:648977
    KISc; Kinesin motor, catalytic domain. ATPase
    cd01366
    Location:646973
    KISc_C_terminal; Kinesin motor domain, KIFC2/KIFC3/ncd-like carboxy-terminal kinesins
    pfam01442
    Location:301443
    Apolipoprotein; Apolipoprotein A1/A4/E domain
    pfam15035
    Location:388543
    Rootletin; Ciliary rootlet component, centrosome cohesion
  15. XM_068214955.1XP_068071056.1  kinesin-like protein KIFC3 isoform X11

    UniProtKB/TrEMBL
    A0A8M3AS77
  16. XM_068214957.1XP_068071058.1  kinesin-like protein KIFC3 isoform X13

    UniProtKB/TrEMBL
    A0A8M9PFZ6
  17. XM_009293854.4XP_009292129.1  kinesin-like protein KIFC3 isoform X14

    See identical proteins and their annotated locations for XP_009292129.1

    UniProtKB/TrEMBL
    A0A8M3B361, A0A8M9PFZ6
    Conserved Domains (4) summary
    smart00129
    Location:566895
    KISc; Kinesin motor, catalytic domain. ATPase
    cd01366
    Location:564891
    KISc_C_terminal; Kinesin motor domain, KIFC2/KIFC3/ncd-like carboxy-terminal kinesins
    pfam15619
    Location:208386
    Lebercilin; Ciliary protein causing Leber congenital amaurosis disease
    cl01090
    Location:362407
    SlyX; SlyX
  18. XM_068214956.1XP_068071057.1  kinesin-like protein KIFC3 isoform X12

    UniProtKB/TrEMBL
    A0A8M9PAK5
  19. XM_068214960.1XP_068071061.1  kinesin-like protein KIFC3 isoform X15

    UniProtKB/TrEMBL
    A0A8M9PFZ6
  20. XM_068214959.1XP_068071060.1  kinesin-like protein KIFC3 isoform X15

    UniProtKB/TrEMBL
    A0A8M9PFZ6